Terms Flashcards
nonmalfeasance
duty to do no harm
beneficence
actively promoting good
autonomy
self-determination and the ability to act on one’s own
justice
being fair or equal in one’s action
additive effects
combo of 2/+ drugs is equivalent to the sum of the individual effects if given alone
1+1=2
biotransformation
metabolism
occurs mainly in the liver and produces a metabolite that is either inactive or active
dependence
compulsive or chronic need
drug-induced teratogenesis
toxic effects of drugs cause congenital anomalies or defects
first-pass effect
initial metabolism in the liver of a drug absorbed from the GI tract
half-life
time required for half of an administered dose of drug to be eliminated by the body
idiosyncratic reaction
abnml and unexpected response that is peculiar to an indv pt
metabolite
chemical form of a drug that is the product of 1/+ metabolic rxn
pharmaceutics
preparing and dispensing drugs
pharmacodynamics
biochemical and and physiologic interactions of drugs at their site of activity
examines effect of the drug
pharmacoeconomics
economi factors impacting cost of drug therapy