terms Flashcards
ankyloglossia
a condition involving atypical, short, thick or tight frenulum that tethers the bottom of the tongue to the floor of the mouth, reducing it’s ROM
AKA Tongue Tie
cleft
abnormal fissure or opening resulting from failure of fusion during embryonic development
dysphagia
swallowing disorder characterized by difficulties swallowing food or liquid
dysrhythmic
irregular rhythm
frenectomy
resection of the lingual frenulum to improve tongue movement
AKA tongue tie clipping
frenotomy
release of the tongue by revising the lingual frenulum with scissors
frenulum
a small fold of tissue that helps secure or restrict the movement of a semi mobile body part. Frenula can be found throughout the body but in the oral cavity it is located under the tongue and between the lips and gums
macroglossia
abnormally large tongue
micrognathia
a condition of having smaller than normal lower jaw
Pierre Robin Sequence
a sequence of abnormalities beginning in utero, primarily consisting of a small lower jaw, a retracted or displaced tongue (glossoptosis) and airway obstruction. Majority of the time, a cleft palate occurs as part of the sequence
glossoptosis
retracted or displaced tongue
peristaltic
wavelike movements of the tongue which assists in removing milk from the nipple and facilitates swallowing
retrognathia
condition having a recession of one or both of the jaws (mandible and maxilla) but more commonly the lower jaw (mandible)
at what GA does rooting reflex appear?
32 weeks
how long does rooting reflex last?
4-6 months (sometimes longer in BF infants)
at what GA does sucking reflex appear?
15-18 weeks
how long does sucking reflex last?
6-12 months
Regulation, Entrainment, Structure, Touch (REST)
intervention associated w/ reduced daily crying and parental stress during infancy
Sudden Unexplained Infant Death (SUID)
sudden death of an infant less than 1 year of age that cannot be explained after a thorough investigation has occurred
acid base dissociation constant (pKa)
factor that determines the likelihood of a drug being trapped in milk compartment, called ion trapping
bioavailability
a measure of how much medication reaches the plasma
dalton
unit used in expressing the molecular weight of proteins, equivalent to atomic mass
diffusion
transfer of molecules of a substance between the plasma compartment and milk compartment
lipid solubility
capability of a substance to dissolve in lipids, fats or oils
milk-to- plasma ratio
tool to evaluate the relative concentration of medication in the plasma compared to the milk compartment
protein binding
degree to which drug binds to proteins within blood plasma, the less bound a drug is, the more efficiently it can traverse cell membranes or diffuse
alveoli
milk producing components of the breast
apoptosis
death of cells that occurs as a normal and controlled part of an organisms growth or development
areola
circular, dark pigmented area that surrounds the nipple
Cooper’s ligaments
connective tissue in the breast that helps maintain structural integrity.
feedback inhibitor of lactation
a small active whey protein that is synthesized by the lactocytes and accumulates in the alveolar lumen
galactopoiesis
maintenance of milk production
involution
removal of milk producing cells after weaning by apoptosis
lactocytes
specialized epithelial cells that line the interior of the alveolus
lactogenesis
process of cellular changes in glandular tissue in the breast whereby mammary epithelial cells are converted from a consecratory state (milk producing) to a secretory state (milk producing)
lactogenesis 1
Differentiation of alveolar epithelial cells into lactocytes that secrete colostrum
lactogenesis 2
the onset of copious milk production that begins 32-96 hours after birth
mammogenesis
development of mammary glands and breast structures from birth through puberty, pregnancy and lactation
montgomery glands
sebaceous glands in the areola surrounding the nipple that make oily secretions to keep the areola and nipple lubricated and protected
myoepithelial cells
cells that encase the alveoli and contract in response to oxytocin to eject milk into ductules
parenchyma
the functional tissue of an organ as distinguished from the connective and supporting tissue
prolactin receptor sites
sites in the lactocytes that allow prolactin to be absorbed from the blood and enter into the alveoli to stimulate milk production
Sheehan Syndrome
a pituitary infarct caused by severe PPH
tail of Spence
Mammary glandular tissue that projects into the axillary region
alpha-lactalbumin
a major whey protein in human milk… it is involved in lactose synthesis
amino acids
the building blocks of proteins
carbohydrate
macronutrient composed of one or multiple sugars
casein
a type of protein found both in solution and suspended in micelles in milk
cholesterol
a member of the group of lipids known as sterols; produced by our bodies and present in foods including human milk
disaccharides
pairs of single sugars linked together
enzymes
proteins that serve as catalysts in biochemical reactions
they facilitate reactions while maintaining their structure and concentration
fatty acid
a type of lipid made of hydrocarbon chain; with a carboxyl group on one end and a methyl group on the other end.
the main component of triglycerides and phospholipids
growth factors
proteins responsible for regulation of a variety of cellular processes, including, but not limited to, cellular growth and differentiation
hormones
chemicals secreted by glands within the body that serve as messengers, acting on other organs to regulate or maintain conditions within the body