Terminology In Medicinal Chemistry Flashcards
(12 cards)
What is Disease?
a disorder of structure or function in a human, animal, or plant, especially one that has a known cause and a distinctive group of symptoms, signs, or anatomical changes.
Define Drug
A drug is any substance or product that is used or intended to
be used to modify or explore physiological systems or
pathological states for the benefit of the recipient
What do you mean by the word Pharmacology?
Science that deals with drugs and their effect on living beings.
✔ Pharmacon = active principle and Logos = a discourse or treatise
✔ Pharmacology covers
✔ a)Physical and chemical properties
✔ b) Biochemical and physiological effects
✔ c) Mechanism of ADME and
✔ d) Therapeutic uses
Pharmacy
Study of formulation and standardization of drugs.
• Covers clinical, scientific, economic and educational aspects of
medical profession
Define Pharmacophore with example
It is the part of the drug molecule that interacts with the receptor and
is responsible for its biological activity.
Example: ibuprofen
Pharmacodynamic
the branch of pharmacology concerned with the effects of drugs and the mechanism of their action.
Pharmacokinetics
the branch of medicine concerned with the uses, effects, and modes of action of drugs.
Metabolites
A substance made or used when the body breaks down food, drugs or chemicals, or its own tissue (for example, fat or muscle tissue). This process, called metabolism, makes energy and the materials needed for growth, reproduction, and maintaining health. It also helps get rid of toxic substances.
antimetabolites
a substance that interferes with the normal metabolic processes within cells, typically by combining with enzymes
agonist
a substance which initiates a physiological response when combined with a receptor.
Antagonist
a substance which actively opposes the physiological activities; an adversary.
Therapeutic index
The therapeutic index is a quantitative measurement of the relative safety of a drug
