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Pathophysiology & Pharmacology 1 > Terminology / Definitions > Flashcards

Terminology / Definitions Flashcards

1
Q

aetiology (etiology)

A

The study of causes of disease.

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2
Q

iatrogenic

A

Caused from medical intervention

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3
Q

idiopathic

A

Of unknown cause

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4
Q

Pathogenesis

A

Mechanism and progress of disease

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5
Q

Epidemiology

A

The study of patterns of health and disease.

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6
Q

Incidence of disease

A

The amount of NEW cases

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7
Q

Prevalence of disease

A

The total number of cases

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8
Q

Morbidity

A

Incidence of disease in a population

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9
Q

Mortality

A

Death rate

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10
Q

Drug

A

Any substance used to modify physiological systems or pathological states for the benefit of the recipient.

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11
Q

Pharmacokinetics

A

The effect of the body on the drug after administration.

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12
Q

Pharmacodynamics

A

The effect of the drug on the body.

Remember TNT - dynamite - blows up the body

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13
Q

Drug tolerance

A

Repeated use of a drug leads to decrease in effect.

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14
Q

Drug dependence

A

Enables day to day survival - eg. Insulin

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15
Q

Tachyphylaxis

A

Diminished responsiveness following repeat dosing of the same drug concentration. Eg. GTN patches.

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16
Q

Adverse drug reaction

A

Unintended response to drug given in normal dose/treatment.

17
Q

Adverse drug event

A

Injury resulting from medical intervention related to a drug, but not caused from the drug itself. Eg, wrong drug given, wrong patient.

18
Q

Adverse effect

A

Unwanted effect resulting from pathway other than the one targeted.

19
Q

Drug affinity

A

Mechanism of binding

20
Q

Drug specificity

A

One target, one effect. How well the drug binds to the target, compared to other receptors.

NB. No drugs claim to have complete specificity.

21
Q

Drug selectivity

A

How well the drug binds to the main target.

22
Q

Potency

A

The amount of drug required to elicit a response.

23
Q

Emax

A

Maximal efficacy (100%)

Pathophysiology & Pharmacology 1 (4 decks)

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