Terminology Flashcards
Medial
Midline
Lateral
Away from midline
Dorsal
Back
Proximal
Toward body
Distal
Away from body
Cranial
Head
Caudal
Toes
Ventral
Front
Transverse
Plane. Split top and bottom.
Frontal
Plane. Split front and back.
Sagittal
Plane. Split left and right.
Diaphysis
Long shaft of bone.
Epiphysis
End of a long bone.
Medullary canal
centre of the bone. Where the marrow is.
Periosteum
Outer layer of bone.
Endosteum
Inner layer of bone.
Metaphysis
Growth Plate
Cement Lines
outer ring of osteon (where fracture propgation occurs)
Haversian Canal
Contain blood vessels.
Lacunae
Holes for osteocytes.
Canaliculi
Channels between lacunae. Hypothesis that for osteocyte communicate.
Volkmann’s Canal
Contans tansverse blood vessels.
Cortical bone
Compact bone (outer layer)
Trabecular bone
Spongey - found at ends of bone
Osteocytes
Communicate with canniculi. Mechanosensitive, detecting microcracks.
Osteoblasts
Lay down bone cells
Osteoclasts
Remove bone
Wolfs Law
Bones adapt to loading
Simple fracture
one break
Comminuted fracture
more than three breaks
Transverse fracture
right angle to bone
Oblique fracture
45 deg to bone
Spiral fracture
Torsion fracture
Greenstick fracture
Young bone - bone bends and doesn’t entirely break.
Elastic behaviour of cartilage
Rapid loading so no fluid flow.
Viscoelastic behaviour of cartilage
Slower loading so fluid flow.
Constitutive Equation
A mathematical expression to determine the experimentally determined stress-strain response.
Integrin
Extends through cell membrane and tell nucleus what is happening via pressure.
De-protein Coupled Receptor
Extends through membrane to cytoskeleton, senses change in pressure.
SAIC
Stretch-Activated Ion Channel. Allows calcium to flow through and changes when pressure changes.
Tissue Grafting
Take cartilage from another source and put a plug where it is needed most.
Autologous Chondrocyte Therapy
Inject cultured chondrocyte cells - often results in fibrocartilage.
Microfracture
Damage subchondral bone to get mesenchymal stem cells that differentiate to chondrocytes.