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Terminologies Flashcards

0
Q

Zone of antibody escess

A

Prozone

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1
Q

It is a reaction that is influenced by the amount of antigen and antibody from the cell-serum mixture; presence of either prozone or postzone often leads to false negative result

A

Zonal reaction

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2
Q

It is a mixture of 0.1 M dithiothreitol plus 0.1% cysteine-activated papain used to dissociate IgG molecules from erythrocytes showing a positive DAT reaction

A

ZZAP

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3
Q

Zone of maximum or greatest reaction

A

Equivalence zone

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4
Q

It is the net negative charge of red cell measured at the surface of shear; if it is reduced, red cells tend to become closer to each other and therefore easier to agglutinate

A

Zeta potential

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5
Q

It is the blood group whose genes are located in the X-chromosome; Xg antigen is seen in greatest frequency among females than males

A

Xg blood group

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6
Q

It is the thick gelatinous substance rich in hyaluronic acid that make up the matrix of the umbilical cord

A

Wharton’s jelly

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7
Q

It is a soluble haptenic forms of A and B antigens capable of neutralizing their corresponding antibodies

A

Witebsky substance

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8
Q

It is the period of time when the disease is present but tested serologically negative

A

Window period

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9
Q

It refers to successive suspension of whole blood with NSS, centrifugation, and finally decanting completely the supernatant fluid. This is preferably done three times

A

Washing

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10
Q

It is a colorless crystalline compound widely used as an anticlotting drug; anticoagulant drug that acts by inhibiting synthesis of Vitamin K dependent factors: II, VII, IX and X

A

Warfarin

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11
Q

Zone of antigen excess

A

Post zone

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12
Q

It is the plasma cell dyscrasia characterized by excessive production of gamma M globulin

A

Waldenstrom’s macroglobulinemia

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13
Q

It is the ability of red cell to survive in vivo after transfusion

A

Viability

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14
Q

Kinds of warfarin

A

Coumadin, Panwarfin, Sofarin

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15
Q

It is a batch test that includes ABO, Rh and antibody screening test

A

Type and Screen (T/S)

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16
Q

It is the transfusion of blood stored in blood bag coming from a homologous donor

A

Indirect transfusion

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17
Q

It is the weaker variant of D-antigen that is detectable only through indirect antihuman globulin test

A

Weak D

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18
Q

It refers to type O and type AB individuals who are considered popularly as universal donor and recipient respectively

A

Universality concept

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20
Q

It is the transfer of blood directly from one person to another

A

Direct transfusion

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21
Q

It is a set of guidelines developed to protect healthcare workers from exposure to infectious agents

A

Universal precaution

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22
Q

It is the reciprocal of the highest dilution that shows a visible reaction

A

Titer

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23
Q

It is the vascular skin reaction commonly signaling allergic reaction

A

Urticaria (hives)

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25
Q

It is the blood transfusion to fetus in utero

A

Intrauterine transfusion

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25
It is used in infants with HDN, it refers to withdrawal of small volume of blood and subsequent replacement with compatible blood
Exchange transfusion
26
It is he adverse reaction happening to a patient following transfusion of a unit of blood or its components
Transfusion Reaction
26
It is the administration of blood or its component intravenously
Transfusion
28
It is a brief loss of consciousness related to fainting
Syncope
29
These are antigens within the ABO group that are weakly expressed thus react less strongly with their corresponding antibody; often, it leads to ABO discrepancy
Subgroup
30
It is the blood taken from a patient to be used for the same patient
Autologous transfusion
31
It is a chemical preservative used in commercial typing sera to prevent bacterial contamination
Sodium azide (0.1%)
32
Kinds of Thiol reagent
DTT (dithiothreitol), 2-ME (2-mercaptoethanol)
33
It is a reagent that can be used to disperse agglutination caused by cold reactive IgM autoantibodies; useful in differentiating IgM from IgG antibodies
Thiol reagent
34
It is the biochemical changes happening on blood upon in vitro storage
Storage lesion
35
Also called as therapeutic apheresis; it refers to removal of blood components for treatment purposes
Therapeutic Phlebotomy
35
It refers to the boundary of the ionic cloud surrounding RBC in saline at which zeta potential is measured
Surface of Shear (slipping plane)
36
It is an inherited characteristic based from gene action
Trait
37
It is a severe physiologic reaction to trauma characterized by pallor, cyanosis, weak rapid pulse, drop in blood pressure which often leads to conciousness
Shock
38
It is the characteristic of the antibody to react with cell expressing the corresponding antigen only
Specificity
39
21 days after collection
ACD, CPD, CP2D
40
35 days after collection
CPDA-1
41
40:1 ratio
Achieved by dropping 2 drops serum to 1 drop 5% red cell suspension
42
In transfusion medicine, it refers to the length of time when blood can still be used before it expires; usually related to the type of anticoagulant used
Shelf life
43
It is a procedure that is done in the tube
In vitro sensitizaztion
44
It refers to the required drops of serum to mix with certain drops of red cell suspension to achieve greater reactivity
Serum to Cell Ratio
45
133:1 ratio
4 drops serum to 1 drop 3% rcs
46
It is the yellowish portion of the blood after clotting or centrifugation which can also be used as a source of antibody
Serum
47
It is a systemic disease caused by the presence of pathogenic microorganisms. Microbes in blood
Septicemia
48
It is the process of allowing interaction or attachment of an incomplete antibody to red cell antigen but no subsequent agglutination reaction seen.
Sensitization
49
It is the group O cells with complete profile of antigens used in antibody detection
Screening cells
50
Reaction that happens intravascularly
In vivo sensitization
51
It is used to determine fetomaternal hemorrhage based on the ability of fetal cells to aggregate around indicator cells
Rosette test
52
I is a method of getting a sample to an individual
Sampling - Pre transfusion sampling - Post transfusion sampling
53
A person who acquire the Se gene either homozygously or heterozygously and is capable of producing ABH substances in secretions
Secretor
54
It is a phenotype of a person who suffers from anemia and whose red cells do not express any Rh antigens
Rh null
56
It is an inherited characteristic showing decreased expression of Rh antigens
Rh mod
57
It is an additional blood bag attached to the primary bag generally intended for component preparation
Satellite bags
57
It is the procedure used to determine blood group soluble substances; this test is used in establishing real blood group if the expression is so weak to be detected by routine cell typing
Saliva testing
58
It is the concentrated purified Anti-D given as a prophylactic to Rh- person who is exposed to D-antigen wither thorugh pregnancy or blood transfusion
Rh Immune Globulin 300 ug of RhIg against 30 ml fetal whole blood or 15 ml of packed cells
59
Other name for Respiratory Distress Syndrome
Hyaline Membrane Disease
60
It is a synonym for antigens in the Rh blood group system
Rh factor
61
It is the disease of unknown cause most frequently seen among premature infants characterized primarily by acute difficulty in breathing
Respiratory Distress Syndrome
62
System of procedures that ensures a laboratory to operate with the most minimal errors.
Quality assurance
63
It refers to the required speed at a given time to sediment particles from a fluid mixture
Relative Centrifugal Force (RCF)
65
It is the group of red cells whose appearance resembles stacks of coins associated with the use of plasma expanders or presence of abnormal plasma proteins
Rouleaux Formation
65
The close monitoring of laboratory operations to allow maximum reliability of test result
Quality control
66
Refers to a person who benefits and receives blood transfusion
Recipient
67
It is the relative strength of an antibody present in a given antiserum usually expressed in titer
Potency
68
Enhances antigen-antibody reaction by concentrating antibody in the mixture through removal of water
Polyethylene Glycol (PEG)
70
2x2 grid used for gene combination
Punnett Square
70
This medium has lower ionic strength that increases the rate of the antibody association. Incubation may be shortened to 5-15 minutes.
Low Ionic Strength Saline Solution: 0.2% NaCl in glycine
71
Extra blood sample collected during whole blood donation from a donor which is intended for serological testing.
Pilot Tube
72
It is any substance that enhances antigen-antibody interaction from a given cell-serum mixture which may be used ro detect low-titered antibodies in routine testing.
Potentiator
73
Synthetic volume expander Crystalloids: Colloids:
: Ringer's Lactate and NSS | : Dextran (6-10%) and HES
74
Positively charged polymer that reduces zeta potential by neutralizing the negative charge in red cell. Useful in the identification of antibodies in the Kidd blood group system.
Polybrene
75
"After child birth"
Post partum
76
It is the inability of the patient to respond favorably after platelet transfusion thus the desired increment in platelet is not achieved.
Platelet refractoriness
77
It is the spontaneous agglutination of the red cells by most normal adult sera regardless of blood group.
Polyagglutination
78
Blood group system showing several allelic forms therefore rendering more than one alternative phenotype.
Polymorphism
78
Plasma derived volume expander:
: Normal Serum albumin- 96% albumin + 4% globulin | : Plasma Protein Fraction- 83% albumin + 17% globulin
80
It is a type of cold autoimmune hemolytic anemia in which a biphasic IgG antibody can be demonstrated with anti-P specificity.
Paroxysmal Cold Hemoglobinuria
81
Products that are transfused in patients suffering from hypovolemia, burn or shock patients.
Plasma Volume Expander
81
Detectable characteristics of genes
Phenotype
82
It is a diagrammatic chart used for illustrating the inheritance patterns of traits in a family study.
Pedigree chart
84
Initial treatment if elevated bilirubin using lights.
Phototherapy
85
It refers to the chance that the alleged father is the biological father.
Paternity Index
86
It is the spontaneous clumping of red blood cells against a given serum.
Panagglutination
87
It is a D antigen that is missing part of its typical antigenic structure.
Partial D
88
It refers to a woman who had at least one pregnancy.
Primiparous
89
It is the group O reagent red blood cells that are used for antibody identification.
Panel cell
90
It is the required temperature which the antibody is most reactive.
Optimum temperature
91
It is a chemical compound formed by a small number of simple carbohydrate molecules.
Oligosaccharide Chain
92
It is any individual who fails to express any antigens on the red cells
Null Phenotype

Blood Banking (1 decks)

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