Term 4-1 Flashcards
L-1
Focused open ended skills consists of which of the following?
Reflection
Non-verbal communication
Silence
Continuers
Reflection
L-1
Non focused, open ended skills consists of which of the following?
Reflection
Echoing
Summarization
Silence
Silence
L-1
In terms of emotion seeking skills, what does the mnemonic FIFE stand for?
Feelings toward the problem
Idea of belief of the cause of the problem
Function or impact of the problem on personal life
Expectation of the disease
L-1
In terms empathy skills, what does the mnemonic NURS stand for?
Name
Understand
Respect
Support
L-2
Mr Smith smoked 1 pack of cigarettes a day for 5 years. What is his number of pack-years?
5
10
15
20
5
L-2
What are the five P’s for sexual history?
Partners Practices Protection STD's Past history of STD's Prevention of pregnancy
L-3
What is hydropic change?
Cell death
Fatty change
Cellular swelling
Cell replication
Cellular swelling
L-3
What is the morphology of irreversible cell injury?
Dilation of the ER
Bleb formation
Small clear vacuoles within the cytoplasm
Vacuolization of mitochondria
Vacuolization of mitochondria
L-4
Give an example of physiological hypertrophy
Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy
Increase in size of uterus during pregnancy
L-4
Give an example of physiological hyperplasia
Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy
Increase in glandular epithelium of breasts during puberty
L-4
Give an example of pathologic hyperplasia
Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy
Enlargement of thyroid
L-4
What are the cardinal signs of inflammation
Heat-calor Redness-rubor Swelling-tumor Pain-dolor Loss of function-function laesa
L-5
Vinca alkaloids arrest the cell in what phase?
Prophase
Anaphase
Metaphase
Telephase
Metaphase
L-5
Statins are an example of what type of drug target
Ion channel
Enzymes
Transporters
Structural Proteins
Enzymes
L-5
Lidocaine targets what
Voltage gated sodium channels
G protein linked receptors
Cytokine receptors
Nuclear receptors
Voltage gated sodium channels
L-6
Marked by exudation of cell poor fluid into spaces created by cell injury or into body cavities describes what type of inflammation
Serous
Fibrinous
Suppurative
Ulcers
Serous
L-6
Which is responsible for opsonization
IgA
IgM
IgG
C5a
IgG
L-7
Which is a non-competitive antagonist
Protamine
Heparin
Aspirin
Ketamin
Ketamin
L-7
Which is a competitive irreversible antagonist
Protamine
Heparin
Aspirin
Ketamin
Aspirin
L-9
Classically activated macrophages are induced by which cytokine
IFN gamma
IL-13
IL-4
ROS
IFN gamma
L-9
Which diseases are characterized by granulomatous inflammation
Tuberculosis
leprosy
Syphilis
All of the above
All of the above
L-9
What is the WBC count for a leukemoid reaction
10000-14000 cells/mL
1000-4000
4001-10000
40000-100000
40000-100000
L-11
Which method of drug administration produces 100% bioavailability
oral
IV
sublingual
anal
IV
L-11
For a weak acid which form is more liposoluble
protonated
unprotonated
protonated
L-11
Weak acids are excreted faster in
alkaline urine
acidic urine
alkaline
L-13
What is the drug given for the treatment of an overdose of acetaminophen?
Digoxin
N-acetylcysteine
Erythromycin
Rifampin
N-acetylcysteine
L-13
Which drug does not increase the transcription of cytochrome P450?
phenobarbitol
aspirin
rifampin
carbamazepine
aspirin
L-12
What is an example of labile tissue
smooth muscle
cardiac muscle
epidermis
neurons
epidermis
L-12
Names the 4 steps to scar formation.
Maintenance of hemostasis
Inflammation
Cellular proliferation
Tissue remodeling
L-14
What are the three main characteristics of an organ affected by amyloidosis?
enlargement
firm
waxy
L-14
What are the 5 main types of amyloids?
B-2 amyloid alzheimer's B-2 microglobulin dialysis AL-lambda light chain B cells AA-liver, chronic inflammatory diseases Transthyretin familia neuropath
L-15
What three drugs display zero order elimination?
aspirin
ethanol
phenytoin
L-15
How many half-lives does it take to attain steady state?
4
L-16
Lipofucsin is
Intracellular/exogenous/inert
Intracellular/endogenous/inert
Extracellular/exogenous/active
Extracellular/exogenous/active
Intracellular/endogenous/inert
L-16
Dystrophic calcification includes
cell injury/death
normal serum Ca++ levels
occurs in coronary artery and breasts
all of the above
all of the above
L-18
What are the characteristics of dysplasia
cellular pleomorphism
nuclear pleomorphism
disordered arrangement of cells
L-18
Give three characteristics of benign tumors
well differentiated
slow growth
does not invade surrounding normal tissue
L-19
N-acetyltransferase 2 catalyzes the acetylation of which drug
succinylcholine
metoprolol
isoniazid
codeine
isoniazid
L-19
Butyrylcholinesterase interacts with which drug
succinylcholine
metoprolol
isoniazid
codeine
succinylcholine
L-20
What are the 3 phases of metastasis
invasion of extracellular matrix
movement thru the interstitial tissue
vascular dissemination and homing of tumor cells
L-20
What enzyme breaks down the extracellular matrix
collagenase
L-21
What is the proper chemotherapy for neoplasms that are not amenable to surgery
primary
adjuvant
neoadjuvant
primary
L-21
Which drug rescues bone marrow from the effects of methotrexate
Mesna
Amifostine
Leucovorin
Amifostime
Leucovorin
L-22
What is a factor of cancer cachexia?
reduced food intake
reduced synthesis and storage of fat
TNF alpha
all of the above
all of the above
L-22
What causes fever?
IL-1
IL-2
IL-4
IL-5
IL-1
L-22
Which immunohistochemical stain is used for epithelium?
desmin
keratin
vimentin
PSA
keratin
L-23
Which drug reduces the cardiotoxicity caused by anthracyclines
dexrazoxane
leucovorin
allopurinol
5-HT
dexrazone
L-23
Which drug potentiates the activity of 5-fluorouracil
dexrazoxane
leucovorin
allopurinol
5-HT
leucovorin
L-24
Which chemical carcinogen is responsible for leukemia
asbestos
nitrosamines
alkylating agents
aromatic amines
alkylating agents
L-24
Which DNA oncogenic virus is responsible for
Burkitt’s lymphoma
HPV
EBV
HBV
H. pylori
EBV
L-25
Which drug is the most likely to cause peripheral neuropathy
vinblastine
6-MP
docetaxel
vincristine
vincristine
L-25
Which drug promotes microtubule polymerization
vinblastine
6-MP
docetaxel
vincristine
docetaxel
L-28
Acute passive venous congestion of the liver can be caused by
Budd-Chiari syndrome
hemothorax
hypovolemic shock
disseminated intravascular coagulation
budd-chiari syndrome
L-28
What are the 5 causes of shock
cardiogenic hypovolemic septic neurogenic anaphylactic
L-29
Omeprazole inhibits which of the below
CYP2D6
CYP2C9
CYP2C19
CYP2C19
L-29
In heparin-induced thrombocytopenia HIT which platelet protein is involved
Platelet Factor (PF) 1
PF-2
PF-3
PF-4
PF-4
L-30
What is a clinical feature of septic shock
cool, pale skin
flushed and warm skin
patient confusion
flushed and warm skin
L-30
What are the three components of virchow’s triad
endothelial injury
abnormal blood flow
hypercoagulability
L-31
In order to be considered a truly bactericidal agent
MBC > MIC
MBC < MIC
MBC = MIC
MBC = MIC
L-31
In order to be considered a bacteriostatic agent
MBC > MIC
MBC < MIC
MBC = MIC
MBC > MIC
L-32
What is a characteristic of a thrombus
platelets not involved
gelatinous
not attached to the vessel wall
lines of zahn
lines of zahn
L-32
What is characteristic of a massive pulmonary thromboembolism
sudden death
dyspnea, pain
asymptomatic
sudden death
L-33
Which drug can be prescribed to children and pregnant women
penicillin G
penicillin V
ampicillin
amoxicillin
amoxicillin
