Term 4-1 Flashcards

1
Q

L-1

Focused open ended skills consists of which of the following?

Reflection
Non-verbal communication
Silence
Continuers

A

Reflection

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2
Q

L-1

Non focused, open ended skills consists of which of the following?

Reflection
Echoing
Summarization
Silence

A

Silence

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3
Q

L-1

In terms of emotion seeking skills, what does the mnemonic FIFE stand for?

A

Feelings toward the problem
Idea of belief of the cause of the problem
Function or impact of the problem on personal life
Expectation of the disease

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4
Q

L-1

In terms empathy skills, what does the mnemonic NURS stand for?

A

Name
Understand
Respect
Support

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5
Q

L-2

Mr Smith smoked 1 pack of cigarettes a day for 5 years. What is his number of pack-years?

5
10
15
20

A

5

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6
Q

L-2

What are the five P’s for sexual history?

A
Partners
Practices
Protection STD's
Past history of STD's
Prevention of pregnancy
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7
Q

L-3

What is hydropic change?

Cell death
Fatty change
Cellular swelling
Cell replication

A

Cellular swelling

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8
Q

L-3

What is the morphology of irreversible cell injury?

Dilation of the ER
Bleb formation
Small clear vacuoles within the cytoplasm
Vacuolization of mitochondria

A

Vacuolization of mitochondria

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9
Q

L-4

Give an example of physiological hypertrophy

Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy

A

Increase in size of uterus during pregnancy

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10
Q

L-4

Give an example of physiological hyperplasia

Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy

A

Increase in glandular epithelium of breasts during puberty

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11
Q

L-4

Give an example of pathologic hyperplasia

Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy

A

Enlargement of thyroid

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12
Q

L-4

What are the cardinal signs of inflammation

A
Heat-calor
Redness-rubor
Swelling-tumor
Pain-dolor
Loss of function-function laesa
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13
Q

L-5

Vinca alkaloids arrest the cell in what phase?

Prophase
Anaphase
Metaphase
Telephase

A

Metaphase

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14
Q

L-5

Statins are an example of what type of drug target

Ion channel
Enzymes
Transporters
Structural Proteins

A

Enzymes

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15
Q

L-5

Lidocaine targets what

Voltage gated sodium channels
G protein linked receptors
Cytokine receptors
Nuclear receptors

A

Voltage gated sodium channels

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16
Q

L-6

Marked by exudation of cell poor fluid into spaces created by cell injury or into body cavities describes what type of inflammation

Serous
Fibrinous
Suppurative
Ulcers

A

Serous

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17
Q

L-6

Which is responsible for opsonization

IgA
IgM
IgG
C5a

A

IgG

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18
Q

L-7

Which is a non-competitive antagonist

Protamine
Heparin
Aspirin
Ketamin

A

Ketamin

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19
Q

L-7

Which is a competitive irreversible antagonist

Protamine
Heparin
Aspirin
Ketamin

A

Aspirin

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20
Q

L-9

Classically activated macrophages are induced by which cytokine

IFN gamma
IL-13
IL-4
ROS

A

IFN gamma

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21
Q

L-9

Which diseases are characterized by granulomatous inflammation

Tuberculosis
leprosy
Syphilis
All of the above

A

All of the above

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22
Q

L-9

What is the WBC count for a leukemoid reaction

10000-14000 cells/mL
1000-4000
4001-10000
40000-100000

A

40000-100000

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23
Q

L-11

Which method of drug administration produces 100% bioavailability

oral
IV
sublingual
anal

A

IV

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24
Q

L-11

For a weak acid which form is more liposoluble

protonated
unprotonated

A

protonated

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25
Q

L-11

Weak acids are excreted faster in

alkaline urine
acidic urine

A

alkaline

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26
Q

L-13

What is the drug given for the treatment of an overdose of acetaminophen?

Digoxin
N-acetylcysteine
Erythromycin
Rifampin

A

N-acetylcysteine

27
Q

L-13

Which drug does not increase the transcription of cytochrome P450?

phenobarbitol
aspirin
rifampin
carbamazepine

A

aspirin

28
Q

L-12

What is an example of labile tissue

smooth muscle
cardiac muscle
epidermis
neurons

A

epidermis

29
Q

L-12

Names the 4 steps to scar formation.

A

Maintenance of hemostasis
Inflammation
Cellular proliferation
Tissue remodeling

30
Q

L-14

What are the three main characteristics of an organ affected by amyloidosis?

A

enlargement
firm
waxy

31
Q

L-14

What are the 5 main types of amyloids?

A
B-2 amyloid alzheimer's
B-2 microglobulin dialysis
AL-lambda light chain B cells
AA-liver, chronic inflammatory diseases
Transthyretin familia neuropath
32
Q

L-15

What three drugs display zero order elimination?

A

aspirin
ethanol
phenytoin

33
Q

L-15

How many half-lives does it take to attain steady state?

A

4

34
Q

L-16

Lipofucsin is

Intracellular/exogenous/inert
Intracellular/endogenous/inert
Extracellular/exogenous/active
Extracellular/exogenous/active

A

Intracellular/endogenous/inert

35
Q

L-16

Dystrophic calcification includes

cell injury/death
normal serum Ca++ levels
occurs in coronary artery and breasts
all of the above

A

all of the above

36
Q

L-18

What are the characteristics of dysplasia

A

cellular pleomorphism
nuclear pleomorphism
disordered arrangement of cells

37
Q

L-18

Give three characteristics of benign tumors

A

well differentiated
slow growth
does not invade surrounding normal tissue

38
Q

L-19

N-acetyltransferase 2 catalyzes the acetylation of which drug

succinylcholine
metoprolol
isoniazid
codeine

A

isoniazid

39
Q

L-19

Butyrylcholinesterase interacts with which drug

succinylcholine
metoprolol
isoniazid
codeine

A

succinylcholine

40
Q

L-20

What are the 3 phases of metastasis

A

invasion of extracellular matrix
movement thru the interstitial tissue
vascular dissemination and homing of tumor cells

41
Q

L-20

What enzyme breaks down the extracellular matrix

A

collagenase

42
Q

L-21

What is the proper chemotherapy for neoplasms that are not amenable to surgery

primary
adjuvant
neoadjuvant

A

primary

43
Q

L-21

Which drug rescues bone marrow from the effects of methotrexate

Mesna
Amifostine
Leucovorin
Amifostime

A

Leucovorin

44
Q

L-22

What is a factor of cancer cachexia?

reduced food intake
reduced synthesis and storage of fat
TNF alpha
all of the above

A

all of the above

45
Q

L-22

What causes fever?

IL-1
IL-2
IL-4
IL-5

A

IL-1

46
Q

L-22

Which immunohistochemical stain is used for epithelium?

desmin
keratin
vimentin
PSA

A

keratin

47
Q

L-23

Which drug reduces the cardiotoxicity caused by anthracyclines

dexrazoxane
leucovorin
allopurinol
5-HT

A

dexrazone

48
Q

L-23

Which drug potentiates the activity of 5-fluorouracil

dexrazoxane
leucovorin
allopurinol
5-HT

A

leucovorin

49
Q

L-24

Which chemical carcinogen is responsible for leukemia

asbestos
nitrosamines
alkylating agents
aromatic amines

A

alkylating agents

50
Q

L-24

Which DNA oncogenic virus is responsible for
Burkitt’s lymphoma

HPV
EBV
HBV
H. pylori

A

EBV

51
Q

L-25

Which drug is the most likely to cause peripheral neuropathy

vinblastine
6-MP
docetaxel
vincristine

A

vincristine

52
Q

L-25

Which drug promotes microtubule polymerization

vinblastine
6-MP
docetaxel
vincristine

A

docetaxel

53
Q

L-28

Acute passive venous congestion of the liver can be caused by

Budd-Chiari syndrome
hemothorax
hypovolemic shock
disseminated intravascular coagulation

A

budd-chiari syndrome

54
Q

L-28

What are the 5 causes of shock

A
cardiogenic
hypovolemic
septic
neurogenic
anaphylactic
55
Q

L-29

Omeprazole inhibits which of the below

CYP2D6
CYP2C9
CYP2C19

A

CYP2C19

56
Q

L-29

In heparin-induced thrombocytopenia HIT which platelet protein is involved

Platelet Factor (PF) 1
PF-2
PF-3
PF-4

A

PF-4

57
Q

L-30

What is a clinical feature of septic shock

cool, pale skin
flushed and warm skin
patient confusion

A

flushed and warm skin

58
Q

L-30

What are the three components of virchow’s triad

A

endothelial injury
abnormal blood flow
hypercoagulability

59
Q

L-31

In order to be considered a truly bactericidal agent

MBC > MIC
MBC < MIC
MBC = MIC

A

MBC = MIC

60
Q

L-31

In order to be considered a bacteriostatic agent

MBC > MIC
MBC < MIC
MBC = MIC

A

MBC > MIC

61
Q

L-32

What is a characteristic of a thrombus

platelets not involved
gelatinous
not attached to the vessel wall
lines of zahn

A

lines of zahn

62
Q

L-32

What is characteristic of a massive pulmonary thromboembolism

sudden death
dyspnea, pain
asymptomatic

A

sudden death

63
Q

L-33

Which drug can be prescribed to children and pregnant women

penicillin G
penicillin V
ampicillin
amoxicillin

A

amoxicillin