Teratology Flashcards

0
Q

Meaning of terratos

A

Monster

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1
Q

Principles of teratology( key terms )

A
Genotype of the conceptus
Time of exposure
Mechanism
Manisfeastation
Amount/ dose of teratogen
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2
Q

Mechanism of teratogens

A

Inhibition and enhance cell proliferation

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3
Q

Most critical time of exposure

A

Third to eight AOG

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4
Q

Causative agent of German measles

A

Rubella virus

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5
Q

Causative agent of syphilis?

A

T. pallidum

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6
Q

Causative agent of Chicken pox?

A

Varicella zoster virus

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7
Q

Causative agent of measles?

A

Rubeola virus

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8
Q

Classic representations of CMV infection?

A

Microcephaly and visual impairment

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9
Q

T/F Rubella causes Cataract

A

True

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10
Q

Causes limb hypoplasia and skin scarring?

A

VzV

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11
Q

Transmitted from soil contaminated feces from domsticated animals especially cats

A

Toxoplasma gondii

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12
Q

Threshhold for abnormality in X-ray

A

200 rads

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13
Q

Effect of x-ray?

A

Kills rapidly proliferating cells

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14
Q

Immunomodulatory drug than cause limb defect?

A

Thalidomide

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15
Q

Anti-neoplastic drug that causes anencephaly and cleft lift

A

Aminoptherin

16
Q

Anti-seizure drug causing fetal hydantiin syndrome and facial defect?

A

Diphenylhydantoin

17
Q

Drug that causes neural tube defect

A

Valproic acid

18
Q

Causes urogenital and skeletal abnormalities

A

Trimethadione

19
Q

Malformation caused by lithium

A

Heart malformation

20
Q

SSRI stands for? And is considered as what type of drug?

A

Selective serotonin re-uptake inhibitor; anti depressant

21
Q

Diagnosis of thecroen rump length uses what

A

ULTRASONOGRAPHY

22
Q

Fetal age and growth assesses 3 noted bones:

A

Buparietal diameter of skull
Femur length

-non bone abdomenal circumflex

23
Q

Increase AFP indicates

A

NTD, spina bifida

24
Q

Low AFP

A

Trisomy 21

25
Q

A byproduct of CNS Development

A

ALPHA FETOPROTEIN

26
Q

Omphalocele is diagnosed using

A

UTZ

27
Q

Study for chromosomal error

A

Chorionic villus sampling

28
Q

Amount of chorionic villus sample to be collected?

A

5-30 mg

29
Q

Amount collected in amniocentesis

A

20-30mL

30
Q

Amnicentesis is aided by?

A

UTZ

31
Q

Result of Amniocentesis are released after

A

1-2weeks

32
Q

It is present where fluid accumulated when down syndrome are present

A

Nuchal transluscency