Teratogens Flashcards by Carlos Garcia

Alkylating agents

Absence of digits

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Aminoglycosides

CN VIII toxicity (deafness)

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Carbamazepine

NT defects
Craniofacial defects
Fingernail hypoplasia
Dev delays

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Diethylstilbestrol (DES)

Vaginal clear cell adenocarcinoma

Mullerian anomalies

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Folate antagonists

NT defects

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Lithium

Ebstein anomaly

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Methimazole

Aplasia cutis congenita

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Phenytoin

Lots of shit

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Tetracyclines

Discolored teeth

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Thalidomide

Limb defects

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Valproate

NT defects

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Warfarin

Bone deformities
Fetal hemorrhage
Abortion
Eye probs

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Alcohol

Retardation

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Cocaine

Fetal addiction

Placental abruption

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Smoking

Low birth weight
Preterm labor
Placental probs
ADHD

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Iodine (lack or excess)

Congenital goiter

Hypothyroidism (cretinism)

Maternal diabetes

Caudal regression syndrome
Heart defects
NT defects

Vit A excess

Spont abortion
Cleft palate
Cardiac probs

X-rays

Microcephaly

Retardation

ACE inhibitors

Renal damage