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RSL - Pharmacology > Teratogens > Flashcards

Teratogens Flashcards

1
Q

d

ACE inhibitors

A

Renal damage

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2
Q

d

Alkylating agents

A

Multiple abnormalities; missing digits

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3
Q

d

Aminoglycosides

A

CN VIII damage

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4
Q

d

Carbamazepines

A

Facial dysmorphism, neural tube defects, developmental delay, fingernail hypoplasia

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5
Q

d

Diethylstilbestrol

A

Müllerian duct abnormalities, Vaginal clear cell adenocarcinoma

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6
Q

d

Folate antagonists

A

Neural tube defects

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7
Q

d

Isoretinoin

A

Severe birth defects

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8
Q

d

Lithium

A

Ebstein anomaly

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9
Q

d

Methimazole

A

aplasia cutis congenita (absence of skin)

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10
Q

d

Phenytoin

A

Fetal hydantoin syndrome (cleft palate, cardiac defects, phalanx/fingernail hypoplasia)

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11
Q

d

Tetracyclines

A

Discolored teeth

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12
Q

d

Thalidomide

A

Limb defects (phocomelia, micromelia… flipper baby)

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13
Q

d

Valproate

A

Inhibition of maternal folate–> neural tube defects

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14
Q

d

Warfarin

A

Fetal hemorrhage, Bone deformities, abortion, Opthalmologic abnormalities

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15
Q

d

Alcohol

A

Fetal alcohol syndrome

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16
Q

d

Cocaine

A

Abnormal fetal growth, fetal addiction, placental abruption

17
Q

d

Smoking

A

Low birth weight, preterm labor, placental problems, IUGR, ADHD

18
Q

d

Iodine

A

Congenital goiter or hypothyroidism

19
Q

d

Maternal diabetes

A

Caudal regression syndrome (anal atresion to sirenomelia), congital heart defects, neural tube defects

20
Q

d

Vitamin A

A

Spontaneous abortion, cleft palate,

21
Q

d

X-Ray

A

Microcephaly, intellectual disability

RSL - Pharmacology (1 decks)

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