Teratogenic Agents Flashcards

1
Q

Midazolam

A

Cleft Palate

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2
Q

Cocaine

A

Growth retardation

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3
Q

Safe

A

volatiles (not N2O?)/opioids/paralytics/barbiturates/propofol

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4
Q

N2O?

A

Nitrous oxide is the only inhaled anesthetic that has been shown to be teratogenic to experimental animals, although this was at high concentrations for prolonged periods. It appears that nitrous oxide may inhibit DNA synthesis through its effects of the inhibition of methionine synthase.

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5
Q

Others: A

A

ACE-i, Alcohol, Androgens, Antithyroid drugs

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6
Q

Others: C

A

carbamezepine, chemotherapeutic agents, cocaine, coumadin

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7
Q

Others: D

A

diethylstilbestrol

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8
Q

More: L/M/P/R/S

A

lead, lithium, mercury, phenytoin, radiation (>0.5 Gy), streptomycin/kanamycin,

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9
Q

T’s

A

tertracycline, thalidomide, trimethadione,

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10
Q

V’s

A

valproic acid, vitamin A derivatives

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