TEMA17 virus zoonóticos y fiebres hemorrágicas Flashcards

1
Q

FLAVIVIRUSES (vecteurs)

A

Dengue (Aedes)
West Nile Virus (Culex)
Fiebre amarilla (Aedes)

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2
Q

FLAVIVIRUSES patógenesis

A

el virus se disemina sistemáticamente (sangre) a diferentes organos => enfermedad final dependiendo del órgano afectado:

WNV: SNC => encefalitis
YFV: hígado => hepatitis
DENV: sangre => enfermedad hemorrágica

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3
Q

FILOVIRUSES

A

Virus Marburg (Orthomarburg-virus)
Virus Ebola (Orthoebolavirus)

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4
Q

TTO Ebola

A

mAb114 (mAb humano)
REGN-EB3 (mAb murino humanizado)

vacunación por rVSV-vectored vaccine expressing Ebola surface glycoprotein (“ring vaccination”)

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