Tema 9. Cáncer de próstata Flashcards

1
Q

Gen relacionado con cáncer de próstata

A

BRCA2

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2
Q

Zona donde más se desarrolla Cáncer de próstata

A

Periférica

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3
Q

Gleason es la suma de…

A

La suma de las puntuaciones del área +grave y el +freq

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4
Q

Indicaciones BIOPSIA cáncer de próstata

A
  • expectativa de vida >10 años
  • PSA >4 y/o
  • Tacto rectal sospechoso
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5
Q

Ttos posibles si BAJO riesgo Ca próstata

A
  • VA
  • WW
  • Braquiterapia
  • PR +/-linfadenectomía
  • RT
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6
Q

BAJO riesgo Ca Próstata

A

PSA <10
Gleason <7
Tacto< T2b

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7
Q

Ttos posibles si MEDIO riesgo Ca próstata

A
  • PR +/- linfadenectomía
  • RT
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8
Q

ALTO riesgo Ca próstata

A

PSA >10
Gleason >7
Tacto >T2b

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9
Q

Tto ALTO riesgo Ca próstata

A

Estudio Extensión (TAC + GAMMAGRAFIA OSEA)

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10
Q

Tto Ca próstata METASTÁSICO

A

1- Castración química (análogos GnRH + Bicalutamida (Antiandrógeno)

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11
Q

Tto posibles si CP Resistente a Castración con nuevas metástasis (CPRCM1)

A
  • Abiraterona
  • Enzalutamida
  • Docetaxel
  • Ra223
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12
Q

Recidiva bioquímica postPR

A

PSA>0,2

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13
Q

Recidiva bioquímica postRT

A

PSA>2+ nadir (nivel más bajo de PSA tras tto)

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14
Q

Progresión bioquímica en Metástasis

A

Aumento PSA en 3 tomas distintas + testosterona <50

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15
Q

Progresión radiológica en Metástasis

A

En gammagrafía:
- empeoramiento mt
- nuevas mt

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