Tech Flashcards

1
Q

How can cannabis help people?

A

While more study is needed, research indicates that cannabis can be helpful with things such as:
Helping to relief pain
Helping to reduce anxiety
Improved sleep
Better overall wellness
Weight loss
Diabetes prevention

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2
Q

How does cannabis relieve aches and pains?

A

Essentially, it blocks the pain pathways in the brain.

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3
Q

What is CBD especially helpful with?

A

Reducing anxiety and helping with sleep.

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4
Q

How does cannabis help with weight loss?

A

It helps the body regulate insulin and boosts its efficiency in managing caloric intake.

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5
Q

How does cannabis help prevent diabetes?

A

It may help stabilize blood sugar levels.

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6
Q

How does cannabis protect the brain?

A

It acts as a neuroprotector.

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7
Q

How would you define/describe Medical Marijuana?

A

Medical marijuana is the therapeutic use of the cannabis plant and comes in various forms, including tinctures, topicals, edibles, vaping, and more.

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8
Q

What are some of the best Strains for Pain?

A

ACDC
Blueberry
Catatonnic
Northern Lights
White Widow

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9
Q

In a nutshell, what is the ECS?

A
  • A network of receptors, lipids, and enzymes.
  • It controls balance (homeostasis) and affects how we respond to cannabis.
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10
Q

How does CBD help dampen THC?

A

CBD is a partial antagonist of the CB1 and CB2 receptors, meaning it can be used to block or dampen THC when used in equal doses.

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11
Q

Is CBD psychoactive?

A
  • CBD is thought to be non-psychoactive, but this is not entirely accurate.
  • CBD affects both dopamine and serotonin receptors, and also “talks” to opioid receptors.
  • CBD is not addictive, but certainly has physiological effects, and therefore could be seen as having psychoactive effects of sorts.
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12
Q

In a nutshell, what are cannabinoids?

A
  • Cannabinoids are like messengers that talk to our body through receptors.
  • Some are made by our body (endocannabinoids), like anandamide and 2-AG. - Some come from plants, especially cannabis (phytocannabinoids), like THC and CBD.
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13
Q

What are the big six cannabinoids?

A

CBD
CBC
CBG
CBN
THC
THCV

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14
Q

What cannabinoids are psychoactive?

A
  • THC
  • CBD is a little bit psychoactive as it comes from old THC.
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15
Q

Tell me about CBG.

A

CBG is like a parent to THC and CBD.

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16
Q

What does THCV do?

A

THCV - changes its effects with different amounts.

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17
Q

In essence, what do cannabinoids do?

A

Cannabinoids tell our body what to do. For example, THC tells your brain you’re hungry.

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18
Q

What are the two types of cannabinoids?

A
  • Phytocannabinoids are made by the cannabis plant.
  • Endocannabinoids are made by the body.
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19
Q

Differences between cannabinoids and terpenes? (5)

A
  • Terpenes have strong smells.
  • Terpenes are found in many plants, cannabinoids mainly in cannabis (with some exceptions).
  • Cannabinoids affect the endocannabinoid system (ECS), terpenes don’t directly impact the ECS.
  • Terpenes can influence the entourage effect and how cannabinoids work in the body.
  • Both cannabinoids and terpenes are types of terpenoids, and terpenes might mimic cannabinoid effects.
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20
Q

What do terpenes do?

A

Terpenes can influence the entourage effect and how cannabinoids work in the body.

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21
Q

What are two types of terpenoids?

A

Both cannabinoids and terpenes are types of terpenoids.

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22
Q

What might terpenes mimic?

A

Terpenes might mimic cannabinoid effects.

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23
Q

What is the cannabimimetic effect?

A

When terpenes approximate the behavior and feeling of cannabinoids without necessarily affecting the ECS directly.

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24
Q

How do terpenes affect the entourage effect?

A

Terpenes affect receptor systems in the body, so they can contribute to the entourage effect.

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25
Q

What is something that is very important to determine the effect a particular cultivar (chemotype) of cannabis has?

A

Terpene makeup of a variety of cannabis is very important to determine the effect a particular strain of cannabis has.

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26
Q

What is the ECS is involved with?

A

The ECS is involved with sleep, appetite, immune function, and virtually every critical life function

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27
Q

Where is the endocannabinoid system (ECS) found?

A

All humans and many animals have an endocannabinoid system (ECS).

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28
Q

What is the ECS a network of?

A

The ECS is a network of receptors, lipids, and enzymes.

29
Q

What does the ECS do?

A

It controls balance (homeostasis) and affects how we respond to cannabis.

30
Q

What is the ECS sometimes referred to?

A

The ECS is sometimes called “the master regulator.”

31
Q

What are the three main parts of the ECS?

A

The ECS has three main parts: endocannabinoids, enzymes, and receptors. (EER)

32
Q

What is CBD known for?

A

cannabidiol (CBD), known for promoting relaxation

33
Q

What is THC known for?

A

THC is known for its intoxicating effects

34
Q

What is CBD short for?

A

Cannabidiol

35
Q

What is THC short for?

A

Tetrahydrocannabinol

36
Q

What happens when the ECS is out of balance?

A

When the ECS is imbalanced, it can lead to problems, even diseases.

37
Q

What is the body’s version of cannabinoids?

A

Endocannabinoids

38
Q

What are the primary endocannabinoids?

A
  • Anandamide (AEA)
  • 2-AG
39
Q

What is anandamide?
What does anandamide do?

A
  • Anandamide is the human body’s naturally occurring THC.
  • It interacts with the body similarly to THC, which induces euphoric highs in many individuals.
40
Q

What does 2-AG do?

A

2-AG can have both pain-killing and anti-inflammatory effects.

41
Q

Where is 2-AG mostly found in humans?

A

At relatively high levels in the central nervous system (CNS).

42
Q

Where do endocannabinoids bind?

A

Endocannabinoids bind to receptors all over the body, including the immune system, nervous system, and skin. (INS)

43
Q

Tell me about the main endocannabinoids.

A
  • Anandamide is similar to THC and makes you feel happy.
  • 2-AG can reduce pain and inflammation, found in the nervous system.
44
Q

Where is 2AG mainly found?

A

The central nervous system (CNS).

45
Q

Where are cannabinoid receptors found?

A

Cannabinoid receptors are found in every cell in the human body.

46
Q

What do cannabinoid receptors make the ECS work like?
Where does this happen?

A

Cannabinoid receptors make the ECS work like a mainframe.
This happens in the central and peripheral nervous systems (CNS and PNS).

47
Q

What do cannabinoids and endocannabinoids, communicate directly or indirectly with?

A

Receptors

48
Q

What receptors do cannabinoids and endocannabinoids communicate directly or indirectly with?

A

A wide range of receptors, including:
CB1
CB2
dopamine
opioid
serotonin
GPR55
many more.
(CCDOSG)

49
Q

Where are CB1 receptors are most dense?

A

CB1 receptors are most dense in the central nervous system (CNS).

50
Q

What is CB1 mainly responsible for?

A

CB1 receptors are mainly responsible for how cannabinoids interact with the brain.

51
Q

Give an example of how CB1 might work.

A

Molecules like THC bind to CB1 receptors and cause psychoactive “high” effects.

52
Q

What causes the psychoactive “high” effects?

A

When molecules like THC bind to CB1 receptors.

53
Q

How exactly do cannabinoids have this “high” effect on brain cells?

A

Cannabinoids that bind to CB1 receptors can decrease the release of two proteins called glutamate or GABA (gamma-aminobutyric acid).

54
Q

What does glutamate do?

A

Glutamate stimulates or excites the nervous system.

55
Q

What does GABA do?

A

GABA calms down the nervous system.

56
Q

Are glutamate and GABA at the same levels usually?

A

No, when glutamate levels are high, GABA levels are often low, and vice-versa.

57
Q

What is the simple glutamate and GABA equation?

A

Glutamate = go, GABA = stop

58
Q

What does THC block the production of?

A

THC blocks the production of GABA.

59
Q

What happens when THC blocks the production of GABA?
What does this create?

A
  • It means that fewer “stop” signals are transmitted.
  • This creates a buildup of the “go” signal glutamate, which can increase the overall amount of dopamine circulating in the body, which then causes a psychoactive “high.”
60
Q

What are several effects the activation of CB1 causes?

A

Impacts our sense of time
Increases appetite and desire for food
Pain-killing or pain-distracting effects
Affects mood (up or down)
Anti-nausea effects
(TAMPA)

61
Q

Where are CB2 receptors mostly found?

A

CB2 receptors can be found most densely in the immune system.

62
Q

What does research indicate CB2 may be most crucial in helping with?

A

CB2 may prove crucial for people with cancerous tumors and precancerous cells.

63
Q

What does CB1 activation affect?

A

THC’s “high” effect
Time perception
Appetite
Mood (up or down)
Pain relief
Anti-nausea
(TAMPA)

64
Q

Where are CB2 receptors found?

A

immune system
some brain cells
the gut
PNS (peripheral nervous system)

65
Q

What system does CB2 activate?
What does that have to do with cancer?

A

immune response
- cell death
- cell development

66
Q

What can CB2 help with?

A

autoimmune disorders
arthritis
pain
inflammation
(AAPI)

67
Q

What role do enzymes play in the ECS?

A

Enzymes help break down cannabinoids and endocannabinoids to stop any excess, to help maintain the ECS balance.

68
Q

What does the ECS do? Give examples.

A

The ECS is involved in regulating many of life’s most essential processes.

This includes:

Reward perception.
Reproduction.
Inflammatory response.
Immune system function.
Appetite.
Pain sensation.
Mood.
Memory.
The pleasurable effects of exercise.
And, of course, mediating the pharmacological and experiential impact of cannabis.
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