TDM

Question 1

Lithium

Answer 1

range: 0.4-1.0 mmol/l

take 12 hrs post-dose

Question 2

Ciclosporin

Answer 2

trough levels immediately before dose

Question 3

Digoxin

Answer 3

At least 6 hours post dose

Question 4

Phenytoin

Answer 4

Does not need to be monitored routinely but trough levels immediately before dose should be checked if:

• adjustment of phenytoin dose
• suspected toxicity
• detection of non-adherence to prescribed medication