TDM Flashcards

1
Q

Note: therapeutic drug monitoring involves measuring trunk concentrations in biological fluids to:

  1. Assess therapeutic compliance
  2. Evaluate efficacy
  3. Investigate drug-induced toxicity
A

Note: therapeutic drug monitoring involves measuring trunk concentrations in biological fluids to:

  1. Assess therapeutic compliance
  2. Evaluate efficacy
  3. Investigate drug-induced toxicity
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2
Q

The study of how genetic variations affect drug response

A

pharmogenomics

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3
Q

examines genetic variations influencing short response and can guide medication situation and dozing

A

pharmacogenetic testing

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4
Q

Factors affecting drug stability in the sample includes____ and ____ we considered during handling

A

temperature and storage conditions

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5
Q

Deals with the relationship between drug concentration in the receptor site in response of tissues to the drug

A

pharmacodynamics

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6
Q

Deals with the relationship between the drug dose and drug blood
levels/how the body handles the drug

A

pharmacokinetics

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7
Q

Lowest concentration of the drug is expected

A

Trough

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8
Q

Collected when the highest the concentration of the drug is expected

A

peak

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9
Q

Time required to reduce the drug into half of its original concentration

A

half-life

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10
Q

time in which the concentration of the drug in the body stays consistent

A

steady state

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11
Q

Fraction of drug that reaches the blood or the circulation

A

bioavailability

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12
Q

Measures how selective the drug is in producing the desired effect

A

Therapeutic index

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13
Q

Lowest concentration of child in the blood that will produce desired affect

A

Minimum dose effet

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14
Q

Lowest concentration of the drug in the blood that will produce adverse effect

A

Minimum lethal dose

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15
Q

Treatment for congestive heart failure and atrial fibrillation flatter

A
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16
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