TCA Cycle

Question 1

how many CO2 are released from the TCA cycle
which steps release them

Answer 1

2
isocitrate -> a-ketoglutarate
a-ketoglutarate -> succinyl-CoA

Question 2

how many NADH are produced by the TCA cycle
which steps release them

Answer 2

3
isocitrate -> a-ketoglutarate
a-ketoglutarate -> succinyl-CoA
malate -> oxaloacetate

Question 3

how many FADH2 are produced by the TCA cycle
which steps release them

Answer 3

1
succinate -> fumarate

Question 4

how many GTP are produced by the TCA cycle
which steps release them

Answer 4

1
succinyl-CoA

Question 5

what are all of the products of one cycle of the TCA cycle

Answer 5

2 CO2
3 NADH
1 FADH2
1 GTP

Question 6

where do glycolysis and the TCA cycle take place

Answer 6

glycolysis - cytosol
TCA cycle - mitochondrial matrix

Question 7

how does pyruvate enter mitochondria

Answer 7

by an antiport mechanism in exchange for OH-

Question 8

how many rounds of the TCA cycle per glucose molecule

Answer 8

two - one per pyruvate

Question 9

what is the ‘preparation step’ that occurs before the TCA cycle

Answer 9

acetyl-CoA formation step
pyruvate -> acetyl-CoA + CO2 + NADH
(does not count as products of TCA cycle)

Question 10

in a dehydrogenase reaction producing NADH which molecule is oxidised and which is reduced

Answer 10

substrate is oxidised
NAD is reduced