TBI Flashcards
What are the levels of injury on the glascow coma scale?
- Mild injury = 13-15 pts
- Mod injury= 9-12 pts
- Severe = less than 9
What factor influences outcome?
Pre morbid state (decreased outcomes associated with previoius injury)
What are the types of of Primary injury?
- Local
- Coup-countercoup
- Polar damage
- Diffuse axonal injury
What are the types of local injury?
- Laceration
- Clot
- Contusion
What is coup-countercoup?
Blow to the skull on one side that causes brain to shift and be damaged on the opposite side:
- Skull pushes brain at same time as it accelerates
- on the opposited side there is momentary vacuum
- When skull stops accelerating vacuum collapses and brain hits skull
What is polar damage?
Result of an accel/decel injury and most commonly hits the frontal and temporal poles. Ocassionally occipital
What is damamged in DAI? and what are the levels of severity?
- Widely scattered shearing damage to axons
- Severity:
- Mild: little defecit
- Mod: wider areal of subcortical matter
- Severe: extends down and in to midbrain and brainstem (coma with posturing and autonomic dysfuntion
What are types of secondary injury?
- Hypoxemic Ischemic Injury-Brain tissue shifted as a result of swelling
- Intractranial hematoma- forms post injury due to cont. bleeding
- Increased ICP (normal <10 mmHg)
- Autodestructive Cellular phenomena (Cell suicide)
What is arterial hypoxemia?
A form of HII that results in much wider damage from anything shutting off O2 in the brain (MI, airway obstruction, arrythmia, PE)
What are the 2 scenarios for intracranial hematoma?
- “Talk and Die”- pt has as period of lucidity then loses consciousness and ultimately dies (due to space occupying lesion)
- Person in coma and has no lucid period-bleeding can go undetected which results in death
what are the 3 types of brain herniations?
Uncal, Central, Tonsillar
Characteristics of Uncal herniation
- Location: Tentorial notch, midbrain
- Cause: mass lesion in temporal lobe or middle fossa
- Structures involved: Hippocampal gyrus and uncus, occulomotor nerve, cerebral peduncle, midbrain ascending reticular activating system, PCA
- Clinical effects: Paresis of nerve 3, hemiparesis, coma, homonymous hemianopsia
Characteristics of Central herniations
- Location: same as uncal
- Cause: mass lesion in frontal, paretiel, or occipital lobe; progression of uncal
- Structures involved: midbrain, pons (causes decerebate rigidity); ascend. retic. activat. syst (coma)
Characterstics of Tonsillar:
- Location: Foramen magnum, medulla
- Cause: mass lesion in posterior fossa, Progression of central herniation
- Structures involved: Cerebellar tonsils (neck pain and stiffnes), Indirect activation pathways (flaccidity), ascend retic. activat. syst (coma), Vasomotor centers (alters pulse, BP, respiration)
What is ACP? How is it treated?
Increase in excitatory neurotransmitters (glutamate) due to activation of calcium dependant enzymes that destroy more tissue. Treat: cooling; hyperbaric O2, free radical scavengers