[TB] Flashcards

1
Q
A

airborne - droplet transmission/inhalation

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2
Q
A

3

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3
Q
A

Active

Latent

Active non-respiratory

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4
Q
A

Mycobacterium tuberculosis

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5
Q
A

The calcified necrotising focus of TB associated with a lymph node

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6
Q
A

Mantoux test

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7
Q
A

Ziehl-Neelsen

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8
Q
A

Ghon complexes - caseating granulomata

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9
Q
A

increased O2 tension - aerobic bacteria

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10
Q
A

consolidation

calcification

cavitation

fibrosis

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11
Q
A

Apices

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12
Q
A

cavitating TB eroding into blood vessels

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13
Q
A

cavitating TB eroding into bronchioles –> cough –> droplet infection

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14
Q
A

identification of Rifampicin (+multidrug) resistance

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15
Q
A

miliary TB (millet seed - lung invasion)

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16
Q
A

disseminated haematogenous invasion and spread

17
Q
A

Retinal TB

18
Q
A

milary

19
Q
A

Potts

20
Q
A

vertebral TB of the spine

21
Q
A

Potts diseas of the spine (spinal TB)

22
Q
A

NO - continue course regardless of -ve MC&S if hist and clin picture are indicative

23
Q
A

8 hours

24
Q
A

BCG

(wanes during adulthood)

25
Q
A

TB

26
Q
A

CXR

27
Q
A

Trachea pulled towatrds consolidation (away from effusion)

28
Q
A

Isoniazid (-cidal)

Rifampicin (-cidal)

Pyrazinamide (-cidal)

Ethambutol (-static)

29
Q
A

H+R+Z+E

30
Q
A

10 months (penetration - BBB)

31
Q
A

6 months

32
Q
A

hepatotoxicity

peripheral neuropathy

drug-induced lupus

33
Q
A

Hepatotoxicity

Orange discolouration/urine

CyP450 inducer

Interstitial nephritis

34
Q
A

Hepatotoxicity

Gout

Rash

35
Q
A

occular toxicity - optic neuritis

Rash

36
Q
A