TB Flashcards
What is the initial phase of TB treatment
Rifampicin
Isonazid
Pyrazinamide
Ethambutol
Goes for TWO months
What is the continuation treatment of TB
Rifampicin
Isonazid
FOR 4 MONTHS
How do you treat latent TB
3 months of rifampicin + Isonazid OR 6 months of Isonazid
What else may be prescribed for TB
Pyridoxine ( vitamin B6) is also used alongside Tb medication to prevent tingling and numbness of the hands and feet
What should be monitored before taking TB medication
Patients with latent TB aged 35-65 should be cleared of hepatotoxicity
What is the side effect and interactions of Rifampicin
Discolours soft contact lenses and bodily fluids orangey- red colour
Interactions
Enzyme inducer - CYP450 interaction
What is the side effects and interactions of Isonazid
Peripheral neuropathy- give prophylactic pyridoxine (vitamin B6)
Interactions
Enzyme inhibitor- cyp450 interaction
Which drug is hepatotoxic
Pyrazinamide
Which drug causes visual impairment and ocular toxicity
Ethambutol