TB Flashcards
1
Q
Extrapulmonary TB
A
- Lymph node TB
- commonest after lung
- usually extrathoracic
- firm, non-tender cervical/supraclavicular node enlargement
- central necrosis (Central Caseating lesion) → fluctuant
± sinus tract w purulent discharge - cold abscess (X erythema)
- Caseation and calcification of cervical lymphadenopathy may be highly suggestive but is not pathognomonic of TB.
- CNS TB
- TB meningitis — Hydrocephalus is a common finding, may be associated with Cranial nerve Palsy
- Abdominal TB
- Features suggestive of abdominal TB are ascites (79%), enlarged LN (35%) omental thickening (29%) and bowel wall thickening (25%).
- Genitourinarry TB
- IVU can demonstrate the ‘moth-eaten’ calyx which may be the earliest evidence of renal TB.
- TB of bone & spine
- Pott’s Disease
- Miliary TB
- dt haematogenous spread to other sites
- systemic disturbance
- look for other organ involvement esp CNS
- Pericardial TB
- Skin
2
Q
CXR TB
A
- consolidation ± CAVITATION/ Calcification of Upper lobes (more common in adolescents)
- pleural effusion
- widened mediastinum (hilar, paratracheal lymphadenopathy)
3
Q
CXR TB
A
- consolidation ± CAVITATION/ Calcification of Upper lobes (more common in adolescents)
- pleural effusion
- widened mediastinum (hilar, paratracheal lymphadenopathy)
4
Q
SE rifampicin
A
5
Q
SE isoniazid
A
rash
fever
polyneuropathy (vitamin 6 deficiency)
hepatotoxicity
6
Q
SE pyrazinamide
A
7
Q
SE ethambutol
A
optic neuritis
8
Q
SE streptomycin
A
ototoxicity
allergic rxn
9
Q
Which anti-TB is hepatotoxic?
A
RIP
10
Q
Which anti-TB most commonly cause rash?
A
All tb drugs cause rash
Isoniazid + Pyrazinamide
11
Q
Which anti-TB is assoc with thrombocytopenia?
A
12
Q
TST result
A
13
Q
What is MDR-TB?
A
resistance to both rifampicin and isoniazid
14
Q
What is extensively drug-resistant (XDR-TB)?
A
high level resistance to rifampicin, isoniazid, fluoroquinolones and at least 1 injectable agent such as amikacin, capreomycin or kanamycin
15
Q
factors ass w increased risk of drug resistant TB
A
