Tayside Formulary - Hospital Setting

Question 1

If CURB65 = 0-2, what antibiotics should be given (CAP)?

Answer 1

1g amoxicillin PO three times daily

200mg doxycycline PO on day 1 then 100mg once daily (IF PENICILLIN ALLERGIC)

Question 2

If CURB65 = 3-5, what antibiotics should be given (CAP)?

Answer 2

1.2g co-amoxiclav IV three times daily + 100mg doxycycline PO
500mg levofloxacin IV twice daily (IF PENICLLIN ALLERGIC)

Question 3

In severe HAP/aspiration pneumonia, what antibiotics should be given?

Answer 3

IV amoxicllin + metronidazole + gentamicin

IV Co-trimoxazole + Metronidazole +/- Gentamicin (IF PENICILLIN ALLERGIC)

Question 4

In non-severe HAP/aspiration pneumonia, what antibiotics should be given?

Answer 4

PO Amoxicillin + Metronidazole

PO Co-trimoxazole + Metronidazole (IF PENICILLIN ALLERGIC)

Question 5

What antibiotics should be used for an acute exacerbation of COPD?

Answer 5

1st line: Amoxicillin 500mg three times daily

2nd line: Doxycycline 200mg on day 1 then 100mg daily

Question 6

What antibiotics should be used for native valve endocarditis?

Answer 6

Amoxicillin and gentamycin IV

Question 7

What antibiotics should be used for prosthetic valve endocarditis?

Answer 7

Vancomycin and gentamycin IV, followed by rifampicin PO

Question 8

What antibiotics should be used for drug user endocarditis?

Answer 8

Flucloxacillin IV

Question 9

What antibiotics should be used in a non-severe C.diff infection?

Answer 9

Metronidazole PO 400mg three times daily

Question 10

What antibiotics should be used in a severe C.diff infection?

Answer 10

Vancomycin 125mg four times daily PO +/- IV metronidazole