Task 7 Flashcards

1
Q

What is the functional principle of fNIRS?

A
  • within near-infrared spectrum, light can penetrate skull and reach considereable depth to allow investigation of the cerebral metabolism
  • characterises aletration in intensity of attenuated light at differnet wave lengths (based on changes in oxy-/ and deoxyhemoglobin during neural activity
  • limited spatial resolution
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2
Q

What are optodes (in fNIRS)?

A
  • corrosive free sensors
  • the lioght source (attached to the participants head)
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3
Q

what are advantages of fNRIS?

A
  • good protability + affordability
  • metabolic specificity
  • uses corrosive free sensors
  • non invasive
  • not sensitive to movements
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4
Q

What is the light absorption spectra (in fNIRS)?

A
  • most tissues are transparent to light in the near infrared range (700-1000nm) -> hemoglobin and water absorption are relatively small
  • spectral band (= optical window) describes some wave length that is reflected by hemoglobin
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5
Q

What is the relevance of (de)-oxygenated haemoglobin (in fNIRS)?

A
  • in optical imaging changes in optical properties of tissues are tracked using light in the near-infrared range
  • oxy/ deoxyhemoglobin have characteristic optical properties in the visible and near-infrared light range
  • the change in concentration of these molecules during neurovascular coupling can be measured with optical methods
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6
Q

What is the spatial resolution (in fNIRS)?

A
  • around 1 cm3
  • limited depth penetration (max sensitivity at the cortical surface)
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7
Q

What is the temporal resolution (in fNIRS)?

A
  • medium
  • hundrets of ms
  • limited through hemodynamicdelays (= fMRI)
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8
Q

What are limitations of fNIRS?

A
  • limited spatial resolution
  • optode size requires space for emitting and detecting IR light sources
  • noise through hair
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8
Q

What is the purpose of BCIs?

A
  • hard/ software system that provides a direct communication link between neural activity of brain and computer sofware components
  • can be invasive
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9
Q

What are functional principles of BCI?

A

replaces involvement of the descending motor pathways, PNS and muscles in the execution of motor tasks
- functional data
- rule-based alogrithms
- machine learning algorithm
- input commands
- sensory feedback

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10
Q

What are suitable brain measures of BCI ?

A
  • EEG
  • MEG
  • fMRI
  • NIRS
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11
Q

What are suitable tasks for BCI?

A
  • EEG - P3 (non-inavsive communication)
  • MEG - motor task (real-time BCI)
  • FMRI - Prothese (activity in 2 differnet locations) -> challenge = latency of hemodynamic response
  • Nirs - P3 (ohne gel) -> TMS as alternatvie
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12
Q

What are paradigms of BCI?

A
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13
Q

What are encoding strategies of BCI

A
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14
Q

In BCI: What is the signal to noise ratio?

A
  • in MEG bCI better
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15
Q

What are the data processing steps of BCI?

A
  • multivariate pattern analysis
  • machine learning
  • statistics
16
Q

WHat are the relevant outcome measures of BCI?

A
  • decoding accuracy
  • speed
17
Q

What is the practical value of BCIs?

18
Q

What is the relevance of locked-in-syndrome/ control of external equipment?

A
  • mental drawing article
  • BCI rely on brain signals intentionally generated to encode and intention -> communicate yes/no
  • fNIRS + mental imagery
  • locked in = no body movement + no brain impairment