Targeted Temperature after Cardiac Arrest

Question 1

what is target tempertature?

Answer 1

32-34 degrees Celsius

Question 2

how does therapeutic hypothermia help?

Answer 2

suppresses oxidative stress, apoptosis, inflammation, and early hyperemia and delayed hypoperfusion

Question 3

what patient population was studied in cooling studies?

Answer 3

Initially just VTach and VFib (class A), but it is applied to all cardiac arrests (class C)

Question 4

contraindications to therapeutic cooling

Answer 4

1) tympanic membrane temp <30 on admission
2) comatose before cardiac arrest
3) pregnancy
4) terminally ill anyway
5) inherited blood coagulation disorders