Takayasu's Arteritis Flashcards
What is another term for Takayasu’s arteritis (TAK)?
Puseless disease
What is Takayasu’s arteritis?
It is defined as a condition in which there is vasculitis of the large vessels, including the aorta and pulmonary artery
What are the four risk factors of Takayasu’s arteritis?
Young Age, 10 – 40 Years Old
Female Gender
Asian Ethnicity
Renal Artery Stenosis
What are the seven clinical features of Takayasu’s arteritis?
Fatigue
Headache
Asymmetrical Blood Pressure
Absent/Weak Peripheral Pulses
Aortic Regurgitation
Carotid Bruit
Exertional Limb Claudication
In which region of the body is asymmetrical blood pressure most notable in Takayasu’s arteritis?
Upper limbs
What are the three investigations used to diagnose Takayasu’s arteritis?
Blood Tests
CT Angiography (CTA)
MRI Angiography (MRA)
What are the three blood test results indicative of Takayasu’s arteritis?
Decreased RBC Levels
Increased CRP Levels
Increased ESR Levels
What are the two gold standard investigations of Takayasu’s arteritis?
CT Angiography (CTA)
MRI Angiography (MRA)
What is a feature of Takayasu’s arteritis on CTA and MRA?
There is stenosis of the large arteries or their branches
What are the two pharmacological management options of Takayasu’s arteritis?
Corticosteroids
Immunosuppressants
When are corticosteroids used to manage Takayasu’s arteritis?
They are the first line management option
Name two corticosteroids used to manage Takayasu’s arteritis
Prednisolone
Hydrocortisone
How are corticosteroids used to manage Takayasu’s arteritis?
They are used to reduce large vessel inflammation
When are immunosuppresants used to manage Takayasu’s arteritis?
They are the second line management option
Name four immunosuppressants used to manage Takayasu’s arteritis
Cyclophosphamide
Methotrexate
Azathioprine
Rituximab
