Table--Features of GI carcinoid Tumors

Question 1

Esophageal carcinoid tumor:

-Fraction, mean age, location, size, secretory products, symptoms, behavior, disease associations

Answer 1

-Fraction: <1%
-Mean age: Rare
-Location: Distal
-Size: N/A
Secretory products: N/A
-Symptoms: Dysphagia, weight loss, reflux
-Behavior: N/A
-Disease associations: None

Question 2

Stomach carcinoid tumor

-Fraction, mean age, location, size, secretory products, symptoms, behavior, disease associations

Answer 2

-Fraction: <10%
-Mean age: 55
-Location: Body and fundus
-Size: 1-2 cm, multiple; >2 cm, solitary
Secretory products: Histamine, somatostatin, serotonin
-Symptoms: Gastritis, ulcer, incidental
-Behavior: Variable
-Disease associations: Atrophic gastritis, MEN-I

Question 3

Proximal duodenum

-Fraction, mean age, location, size, secretory products, symptoms, behavior, disease associations

Answer 3

Fraction: <10%
-Mean age: 50
-Location: Proximal third, periampullary
-Size: 0.5-2cm
Secretory products: Gastrin, somatostatin, cholecystokinin
-Symptoms: Peptic ulcer, biliary obstruction, abdominal pain
-Behavior: Variable
-Disease associations: Zollinger-Ellison syndrome, NF-1, sporadic

Question 4

Jejunum and Ileum

-Fraction, mean age, location, size, secretory products, symptoms, behavior, disease associations

Answer 4

-Fraction: >40%
-Mean age: 65
-Location: Throughout
-Size: <3.5 cm
Secretory products: Serotonin, substance P, polypeptide YY
-Symptoms: Asymptomatic, obstruction, metastatic dz
-Behavior: Aggressive!!
-Disease associations: None

Question 5

Appendix

-Fraction, mean age, location, size, secretory products, symptoms, behavior, disease associations

Answer 5

-Fraction: <25%
-Mean age: All ages
-Location: Tip
-Size: 0.2-1cm
Secretory products: Serotonin, polypeptide YY
-Symptoms: Asymptomatic, incidental
-Behavior: Benign!
-Disease associations: None

Question 6

Colorectum

-Fraction, mean age, location, size, secretory products, symptoms, behavior, disease associations

Answer 6

-Fraction: <25%
-Mean age: 60
-Location: Rectum>cecum
-Size: >5cm (cecum); <1cm (rectum)
Secretory products: Serotonin, polypeptide YY
-Symptoms: Abdominal pain, weight loss, incidental
-Behavior: Variable
-Disease associations: None