Table 1-1 Growth Factors Involved in Regeneration and Repair

Question 1

Epidermal growth factor

(EGF)

Answer 1

Mitogenic for Keratinocytes

and

Formation of Granulation tissue

Question 2

Transforming Growth Factor α

(TGF-α)

Answer 2

Growth of Hepatocytes

Question 3

Hepatocyte Growth Factor

(HGF)

aka Scatter factor

Answer 3

Growth of Hepatocytes

AND

Increases cell motility

Question 4

Vascular Endothelial Growth Factor

(VEGF)

Answer 4

Stimulates endothelial cells

and

vascular permeability

Question 5

Platelet-derived growth factor

(PDGF)

Answer 5

Recruitment of immuno and growth factors

Question 6

Fibroblast Growth Factors

(FGF)

Answer 6

Stimulates angiogenesis

Promotes fibroblast growth

and

ECM development

Question 7

Transforming Growth Factor β

(TGF-β)

Answer 7

Inhibits INFLAMMATION

Stimulates ECM synthesis

Question 8

Keratinocyte Growth Factor

(KGF)

Answer 8

Stimulates keratinocytes