t3 Flashcards

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1
Q

robert hooke and cells
what year?
what did he do?

A

year : 1665
he built microscopes to examine thin sections of dried cork samples from plants - names cavities cells

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2
Q

cell theory

A
  • all organisms are made up of cells
  • the cell is the fundamental unit of life
  • cells come from pre-existing cells
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3
Q

prokaryotic cells

A

prokaryotic cells lack a nucleus and have no internal compartmentalization

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4
Q

eukaryotes cells

A

eukaryotic cells have a nucleus and internal membrane-bound organelles

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5
Q

hopaniods

A

-located in membranes of bacteria
- modulate the fluidity of the membrane bilayer
-increase rigidity of the membrane

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6
Q

cholesterol

A
  • found in animal cell membranes
  • both polar and non polar regions
  • impact membrane fluidity
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7
Q

all cells are defined by a cell man brand (lipids)

A
  • lipids found in the cell membrane are phospholipids
  • phospholipids have a hydrophobic tail (non polar region) and hydrophilic head (polar region)
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8
Q

lipid structures micelle

A

formed by phospholipids with large bulky heads and a single hydrophobic tail

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9
Q

lipid structure bilayer

A

bilayers and liposomes are formed by phospholipids with small heads and 2 hydrophobic tails

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10
Q

lipid structure phospholipid

A

when in water phospholipid spontaneously form a liposome, wherein polar heads and non polar tails associate with one another in a bilayer

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11
Q

membranes

A

membranes are self-healing because they will spontaneously reform

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12
Q

membranes are a fluid mosaic

A
  • lipids and proteins are found in the membrane, forming a mosaic
  • pupils are able to move laterally within the membrane
  • lipid movement is affected by the nature of the phospholipid tails
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13
Q

saturated vs unsaturated

A
  • van der waals interactions between the fatty acid tails help stabilize the membrane
  • bc these interactions are weak, membrane lipids are able to move in the plane of the membrane, thus membrane is fluid
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14
Q

cholesterol

A
  • found in many animal cell membranes
  • both polar and non polar regions
  • impact membrane fluidity
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15
Q

cholesterol and fluidity

A

cholesterol acts like a “buffer” for membrane fluidity

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16
Q

proteins in the membranes: transporters and receptors

A
  • transporters that move ions and molecules
  • receptors that allow the cell to receive signals from the environment
17
Q

proteins in the membrane: enzyme and anchors

A
  • enzyme that catalyze chemical reactions in a cell
  • anchors that attach to other proteins such as actins or cytoskeleton that help to maintain cell structure and shape
18
Q

integral proteins

A
  • integral membrane proteins are permanently associated with the membrane and can cross the entire membrane
19
Q

peripheral proteins

A
  • peripheral membrane proteins are temporarily associated with either side of the membrane
20
Q

examples of integral membrane proteins

A
  • sodium-potassium pump
  • aquaporins
  • ATP synthase
21
Q

examples of peripheral membrane proteins

A
  • cytochrome c
  • phospholipase
    glycolipid transfer proteins
22
Q

evidence for the fluid mosaic model: is there movement in the membrane?

A
  • proteins are fluorescently labeled
  • one specific region of the membrane is targeted by a laser and photo bleached
  • researchers than observe the membrane to see if the bleached area remains, or if fluorescent proteins return to the bleached area
23
Q

protein ls do move in the membrane

A
  • fluorescence returns to the bleached area, showing that proteins are mobile throughout the membrane
24
Q

cell membranes

A
  • the cell to the right is a pancreatic cell. the cell is surrounded by a cell membrane which defines the shape and size of the cell
25
Q

is the cell membrane impermeable?

A
  • all cells are enclosed by a plasma membrane that serves as a boundary defining the space of the cell
  • the cell membrane is selectively permeable
26
Q

selective permeability of cell membranes

A
  • freely permeable: small gas molecules such as oxygen, nitrogen, and co2
  • somewhat permeable: small, uncharged polar molecules such as water, ethanol, and glycerol
  • impermeable: large, uncharged polar molecules such as glucose and sucrose
  • ions such as h+, na, k, cl, etc
27
Q

simple diffusion: passive transport across the permeable membrane

A
  • movement of molecules from an area of high conc to an area of low conc
  • passive transport does not require expenditure of energy from the system
28
Q

osmosis

A

-water movement across a permeable membrane (ie. diffusion specific to water)
- movement of water from an area of low solute to high solute

29
Q

facilitated diffusion (energy not required) ; movement down a concentration gradient through a channel or carrier

A
  • during facilitated diffusion in cells, molecules and substances move from high conc to low conc throughout transporters embedded in the membrane
30
Q

active transport

A
  • when cells need to move substances against their conc gradient, energy must be expanded
31
Q

primary active transport

A
  • in primary active transport, the na/k pump uses energy released from hydrolysis of atp to move 3 na ions and 2k ions against the conc gradient
  • energy stored in the conc gradient can produce an electrochemical gradient to drive the movement of other molecules through secondary active transport
32
Q

secondary active transport

A
  • antiporter: h ions return into the cell to exchange for the export other positive ions or molecules such as na
  • because the movement of the coupled ions or molecules is driven by the movement of protons and not atp, the transports is called secondary active transports
33
Q

maintaining cell shape

A
  • cell shape and size in red blood cells change based on the solute conc surrounding the cells
  • red blood cells use active transports of ions to keep the internal environment of the cell isotonic to the external environment
34
Q

maintaining cell shape part 2

A
  • in some single-called organisms, cells contain a contractile vacuole, an organelle
  • the contractile vacuole absorbs excess water in the cell and expels it to prevent cell lysis
35
Q

maintaining cell shape: cell walls

A
  • the cells of many different organisms contain a cell wall, a structure that helps to maintain the cell shape
  • the cell wall can be made up of many different compounds but the function of the cell wall is similar in each organism with the structure
36
Q

cell walls and turgor pressure

A
  • the cell wall provides structural support and protection
  • turgor pressure within the cell occurs when water moves into the cell through osmosis
37
Q

plant cell that animal cell doesn’t have

A
  • cell wall: provides additional support to the cell
  • vacuoles: contribute to the structure of the cell by maintaining turgor pressure
  • chloroplasts: convert the energy from sunlight into chemical energy that the cell can use
38
Q

cell organelles: the nuclear envelope

A
  • the nuclear envelope is a double membrane that surrounds the nucleus
  • the membrane is perforated by protein openings called nuclear pores, which allow molecules to move into and out of the nucleus
  • these pores are essential for the nucleus to communicate with the rest of the cell