T&O round 2 Flashcards
Name three functions of bone
Mechanical - protect delicate tissues and organs, a framework for the shape of the human body, form a basis for movement.
Synthetic - haemopoiesis.
Metabolic - mineral storage (ca2+, po4-), fat storage (yellow bone marrow), acid-base homeostasis by absorbing salts to regulate blood pH
What is the difference between endochondral ossification and intra-membranous ossification?
Endochondral - form long bones from cartilage templates. Have continued lengthening by ossification at the epiphyseal plates. Intra-membranous ossification - the formation of bone from clusters of mesenchymal stem cells in the centre of bone.
Describe a coronal section of mature bone
Compact/cortical bone on the outside/external surface. Cancellous bone/spongy on the inside - combines strength with lightness.
Name a factor which affects bone stability
Activity of osteocytes (can act as osteoblasts or osteoclasts).
Activity of osteoblasts (stimulated by calcitonin, GH, oestrogen, testosterone, thyroid hormones, vit A)
Activity of osteoclasts (increased by PTH).
Nutrition - vit D, C, K and B12.
In a fracture repair, first comes hematoma formation. Next comes ______(1)_______, followed by bony callus formation and ______(2)________.
(1) - fibrocartilaginous callus formation - here, the pro callus of granulation tissue is replaced by a fibrocartilaginous callus where bony trabecular are developing.
(2) - bone remodelling - cancellous bone is replaced by compact, cortical bone until bone remodelling is complete.
Define osteomalacia
Softening of bone due to vitamin D deficiency. This increases the risk of bone fractures in older adults.
Describe the four features of OA on XRAY
Subchondral sclerosis, narrowing of joint space, osteophytes, bony cysts (SNOB)
How may OA present?
Deep aching pain in the joint which is exacerbated by use. Reduced range of motion. Grinding sensation/sound. Stiffness during rest - morning stiffness usually lasts less than an 30mins.
Define OA
Degeneration of joint cartilage and underlying bone
Name categories of secondary OA
post-traumatic, post-operative, inflammation/infection related, miscellaneous
What may you find on examination of someone with OA?
Swelling of joint, joint deformity, tenderness on palpation, joint effusions, restricted/reduced movements, joint instability, weakness or wasting
To be considered for a knee replacement, what three features need to be present during a knee examination?
Correctable varus, full extension of the leg (at the knee), and flexion of at least 100 degrees
What management options are available for OA?
Analgesia (e.g. NSAIDS - ibuprofen 200mg, naproxen 500mg initially, then 250mg every 6-8 hours as required). Steriodal injection. Weight loss. Use of walking stick. Surgery - partial or total knee replacement.
Define a Smiths fracture
Fracture of the distal radius with palmar angulation of the distal fracture fragments. Have volar (anterior) displacement of the distal fragment of the radius. AKA a reverse Colles fracture. Usually occurs on fall on back of flexed wrist
Define a Colles fracture
Extra-articular distal radius fracture with dorsal angulation and dorsal displacement. Within 2cm of articular surface.
Describe presentation (Hx and examination) of Colles fracture
Hx of trauma, FOOSH. Immediate pain, tenderness, swelling, bruising. Elderly woman or young adult. PMH of osteoporosis, post menopause. Dinner fork deformity. Unable to grasp object. Increased angulation of distal radius.
Describe presentation of Smiths fracture
Hx of falling on back of hand, or direct blow to the dorsal aspect of the wrist. Young male after high energy fall or elderly female after low energy fall.
Present with pain, swelling on anterior side. Reduced ROM, distal forearm deformity
What are the five signs of compartment syndrome?
5Ps. —> Pain, Pallor, Parasthesia, Pulselessness, Paralysis
What management options are available for fractures of the distal radius?
Reduction - external and/or internal fixation, percutaneous pinning, bone substitiutes. Immobilisation. Physiotherapy to restore range of movement, motion and function.
What are the risk factors for Smiths or Colles fractures?
Age (older than 60 increases risk), being female, osteoporosis, menopause, smoking, alcohol use, prolonged steroid use.
Why does prolonged steroid use increase the risk of fractures?
Steroids decrease osteoblast activity and increase osteoclast activity. This reduces bone density and increases risk of osteoporosis. Increased risk of osteoporosis = increased risk of fracture.
Describe the presentation Dupytren’s disease
Hx of slow progression over years. Nodules present on palm of hands. Nodules are fixed. Nodules have thickened and can form tough cords under skin, fingers are pulled inwards towards palm. May also present with thickened skin on the feet or penis.
How does Carpal tunnel syndrome present?
Pain, numbness and parasthesia in the lateral 3.5 digits. Worse during the night. Pain subsides on shaking wrist. Wasting of thenar eminence, weakness of thumb abduction
What initial investigations would you do for suspected CT?
Tinel’s test - percuss over median N. Phalen’s test - hold wrist in full flexion for a minute. Both tests bring on symptoms.