T Helper Subsets

Question 1

What induces TH1 (2)

Answer 1

IFN gamma, IL-12

Question 2

What STATs are used for TH1

Answer 2

STAT4/1

Question 3

What transcription factor is important for TH1

Answer 3

Tbet

Question 4

What is produced via TH1

Answer 4

IFN gamma

Question 5

What induces TH2

Answer 5

IL-4

Question 6

What STAT is used for TH2

Answer 6

STAT6

Question 7

What transcription factor is important for TH2

Answer 7

GATA3

Question 8

What is produced via TH2 (3)

Answer 8

IL-4, IL-5, IL-13

Question 9

What induces TH17

Answer 9

IL-23, IL-1b

Question 10

What STAT is used for TH17

Answer 10

STAT3

Question 11

What transcription factor is used for TH17

Answer 11

RORgt

Question 12

What is produced by TH17 (4)

Answer 12

IL-17, IL-21, IL-22, IL-26
Think of a dog net nun nacho. The nun is chasing the dog while trying to hold onto a nacho. Luckily for her, the dog gets caught in a net

Question 13

What induces TFH

Answer 13

IL-6, IL-21
Sushi and net
Think of woman’s follicle dragging a net full of sushi

Question 14

What STATs are used for TFH

Answer 14

STAT 3/4/1

Question 15

What transcription factors are used for TFH

Answer 15

Bcl6, IRF4

Question 16

What is produced by TFH (3)

Answer 16

IL-21, IL-4, IL-10
Sir (knight), net, dice

The induction, remember, was a follicle running around with sushi in a net. Here the follicle copulates with a knight who has his own net full of dice

Question 17

What induces Treg

Answer 17

TGFb, IL-2

Question 18

What STAT is used by Treg

Answer 18

STAT5

Question 19

What transcription factor is used in Treg

Answer 19

FOXP3

Question 20

What is produced by the Treg pathway (2)

Answer 20

TGFb, IL-10