t/f mixed Flashcards
- Acral lentiginous melanomas is the commonest form of melanoma is non-Caucasians.
True
Pemphigus is most common in the elderly and is characterized by sub-epidermal blisters.
False. It’s characterized by superficial blisters. Sub-epidermal blisters = bullous pemphigoid
Bronchopneumonia is characterized by diffuse consolidation of an entire lobe.
False. Characterised by patchy consolidation of several lobes
Lobar pneumonia is rarely associated with sputum production.
False. It is commonly associated with sputum production
Lobar pneumonia is rarely through the stages of red hepatisation before grey hepatisation.
False. It is always through those stages.
Opportunistic lung infections with Pneumocystis jirovecii show alveoli with bubbly pink exudates.
True
Primary tuberculosis usually affects the lungs bilaterally and involves apices.
False, secondary tuberculosis is nearly always located in the lung apices and sometimes bilaterally.
Lymphocytic infiltration and follicular destruction are the histologic hallmarks of Graves disease.
False. Those are hallm,arks of autoimmune hypothyroidism
Hypothyroidism can be associated with peripheral fungal infections and an enlarged edematous tongue
True. They are prone to candida albicans
Autoimmune hypothyroidism is the most common cause of hypothyroidism and is usually seen in older women.
True
Different types of thyroid cancers tend to affect different age groups
True
Malignant melanomas always contain melanin
False. They can be various colours
A TSH-secreting adenoma is associated with high serum concentrations of T3, T4 and TSH.
True
Tuberculosis is an example of granulomatous inflammation without necrosis
False. There is necrosis in primary TB with granulomatous inflammation
. A Reed-Sternberg cell (R-S cell) is derived from B-lymphocytes and is the characteristic cell of non-Hodgkin’s lymphomas
- False, it is the characteristics of Hodgkin’s lymphomas.
Anemia could be indicative of a more sinister disorder such as acute leukemia.
True, having acute leukemia with normal hemoglobin and white blood cell counts is extremely rare.
Multiple myeloma defined as a neoplastic proliferation of neutrophils.
False. Its a neoplastic proliferation of PLASMA cells
The major clinical features of multiple myeloma are osteonecrosis and pathological fractures.
- False, as osteoporosis with pathological fractures is most common skeletal abnormalities in multiple myeloma, the major clinical feature of the disease is BONE PAIN
Oesophageal varices are not a feature of portal hypertension.
False
Hepatocyte injury in alcohol liver disease is caused by acetaldehyde.
True
Hepatocellular carcinoma is often associated with raised serum levels of alpha-fetoprotein.
True
Auto-immune hepatitis occurs more commonly in males.
False. Mostly in females
The serum level of caeruloplasmin is decreased in Wilson’s disease.
True
Staphylococcus aureus is the most common cause of bacterial endocarditis in intravenous drug users.
True.
Papillary muscle rupture causes acute mitral valve incompetence with resultant cardiogenic shock and death within 48 hours.
True
Mitral stenosis is a complication of Rheumatic heart disease.
True
Right to left cardiac shunting is characterized by early cyanosis.
True
A cardiac aneurysm develops in areas of prior myocardial infarction and may predispose to development of systemic emboli.
False. POST-myocardial infarction
BRCA mutations are linked with hereditary breast cancer.
True
Metastatic breast cancer to lymph nodes does not affect the prognosis of patients
False
HPV causes cervical cancer
True
An osteochondroma is a benign neoplasm and comprises of bone with a cartilage cap.
True
Osteosarcoma, a malignant neoplasm of bone, is mainly seen in young males, and commonly metastasises to regional lymph nodes.
False. lung and bones are the most common metastatic sites. To lymph node is rare.
Codman’s triangle is a radiographic description of slow growing bone lesions that typically elevate the periosteum.
True, osteosarcoma is the slow growing bone lesion.
Rheumatoid arthritis affects the weight bearing joints.
False, that is osteoarthritis
Rheumatoid arthritis is associated with high serum concentrations of Rheumatoid Factor (RF) and may be linked to other autoimmune conditions
True
Primary hyperparathyroidism is an important cause of osteoporosis.
True
Addison’s disease is the most common cause of adrenal insufficiency worldwide.
true
Primary tuberculosis may involve the adrenal glands with resultant inflammation (tuberculous adrenalitis) and loss of adrenal-cortical function (adrenal insufficiency).
True
General weakness, vitiligo and salt craving are commonly seen in Addison disease.
True