T Cells

Question 1

acquired immune response includes the following features

Answer 1

specificity, diversity, memory, self/non-self discrimination (imperfectly)

Question 2

Primary immune response responds to

Answer 2

antigens

Question 3

secondary immune response responds to

Answer 3

tissue grafting

Question 4

TCR structure

Answer 4

heterodimer with an alpha and beta chain, or occasionally gamma and delta

Question 5

BCR structure

Answer 5

cluster of molecules involving surface immunoglobulin, usually IgM or IgD, coupled with disulfide bonded heterodimers IgAlpha and IgBeta

Question 6

B cell receptors cannot stimulate the cell without

Answer 6

accessory molecules!

Question 7

CD21

Answer 7

complement receptor for EBV, induces malignancy, uncontrolled growth of B cells

Question 8

role of the thymus

Answer 8

maturation of T cells

Question 9

CD3 complex

Answer 9

T cell receptor, activate both cytotoxic and helper T cells

Question 10

life span erythrocytes

Answer 10

120 days

Question 11

life span neutrophils

Answer 11

days or weeks

Question 12

life span lymphocytes

Answer 12

years

Question 13

positive recruitment

Answer 13

hematopoietic growth factors and cytokines will recruit cells from progenitors, can also undergo cell death

Question 14

leukocytes

Answer 14

white cells responsible for both adaptive and innate immune responses

Question 15

lymphocytes

Answer 15

B and T cells and NK cells, specialized leukocytes, diversity, specificity, memory, recognize non-self

Question 16

NK cells

Answer 16

lymphocytes without antigen receptors, placing them in the innate immunity category. They need antibodies present to work.

Question 17

antibody dependent cell-mediated toxicity

Answer 17

carried out by NK cells, but requires the presence of antibodies

Question 18

MHC molecules contain

Answer 18

a self-antigen and a foreign antigen in the case of infection

Question 19

MHC class I is regulated by

Answer 19

cytokines (alpha, beta, or gamma)

Question 20

MHC class I works to

Answer 20

activate killer T cells that destroy and kill infected cells

Question 21

MHC class II works to

Answer 21

activate helper T cells which stimulate appropriate