T-Cell Mediated Immunity

Question 1

What makes up the TCR complex? [3]

Answer 1

Zeta protein
TCR
CD3

Question 2

Function of TCRs that have delta and gamma chains instead of alpha and beta chains.

Answer 2

Recognized protein and non-protein antigens not displayed by classic MHC molecules

Question 3

Molecular basis for SCID (Severe combined immunodeficiency) syndrome also called Bubble boy syndrome.

Answer 3

Deficiency of RAG-1 and RAG-2 enzymes resulting in impaired production of T cells and NK cells as well as reduced function of B cells