Systemic Vasculitis

Question 1

Name 2 small vessel vasculitis

Answer 1

microscopic polyangitis
granulomatosis with polyangitis
eosinophilic granulomatosis with polyangitis
Henonch Schonlein Purpura

Question 2

Name one medium vessel vasculitis

Answer 2

Kawasaki

Polyarteritis nodosa

Question 3

Name one large vessel vasculitis

Answer 3

Giant cell arteritis

Takayasus arteritis

Question 4

Which small vessel vasculitis is not ANCA +

Answer 4

Henoch Schonlein Purpura

Question 5

2 associations with polymyalgia rheumatica

Answer 5

HLA-DR4

IL-6

Question 6

Polymyalgia rheumatic examination findings

Answer 6

decreased shoulder abduction
distal synovitis
decreased range of movement
normal muscle strength

Question 7

Polymyalgia rheumatica investigation findings

Answer 7

increased ESR/CRP
Increased ALP
CK normal
Anti-CCP/RF/ANA NORMAL

Question 8

Treatment for polymyalgia rheumatica

Answer 8

prednisolone 10-15mg

Question 9

Symptoms of giant cell arteritis

Answer 9

headache 
double vision 
vision loss
jaw claudication 
tender scalp
dizzy

Question 10

Examination findings in giant cell arteritis

Answer 10

superficial temporal artery inflammation
erythema
tender to palpate
bruits

Question 11

Investigation findings for giant cell arteritis

Answer 11

ESR/CRP raised
increased ALP

USS: increased diamter of superfifical temporal artey and hypoechoic wall thickening (halo)

Biopsy: T lymphocytes, giant cells in vessel wall. Granulomatosis infltration of intima and media.

Question 12

Treatment of giant cell arteritis

Answer 12

Prednisolone 4-60mg