Systemic Derm mainfestations Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Lupus

A
  • butterfly rash (malar rash)

- Due to trapping of immune complexes in capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Progressive Systemic Sclerosis (Scleroderma)

A

aka statue disease
Inflammatory, vascular and sclerotic changes of the skin and various internal organs
Most prominent clinical feature:
Thickening of the skin= scleroderma
Loss of joint mobility, contracture development, dry skin, hair loss
-think mask facies or shiny/stretched skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

90% of scleroderma pts will have….

A

Raynaud’s phenomenon (a pale-blue-red sequence of color changes of the digits, most commonly after exposure to cold)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CREST syndrome

A

associated w/scleroderma
Cutaneous Calcinosis (Ca deposits in fingers)
Raynaud’s phenomenon
Esophageal dysfunction
Sclerodactyly (scleroderma limited to the fingers)
Telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

scleroderma tx

A
  • immunosuprresion

- specific organ tx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Polymyositis & Dermatomyositis

A

Bilateral proximal muscle weakness & skin manifestations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

cutaneous manifestations of dermatomyositis

A

A dusky, purplish red rash is important diagnostic finding
face, scalp, neck, shoulders, upper chest and back (photosensitive)
Periorbital heliotrope of upper eyelids with or without edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

sarcoid

A
  • noncaseating granulomas in multiple organ systems
  • presents w/pulmonary symptoms
  • Erythema nodosum is the most common nonspecific cutaneous lesion
  • “great imitator”
  • “apple jelly” plaques
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

pemphigus vulgaris

A
  • Uncommon epidermal blistering condition that typically begins in the mouth
  • positive nikolsky sign
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

bullous pemphigoid

A
  • Chronic blistering eruption usually in elderly patients
  • large bulla
  • negative nikolsky sign
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

dermatitis herpetiformis

A
  • Extremely itchy grouped vesicles usually on extensor surfaces
  • related to gluten intolerance
  • tx w/dapsone to decrease inflammation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly