Systemic conditions causing eye signs Flashcards
What is anterior uveitis/iritis?
Inflammation of the front chamber of the eye
What is posterior uveitis/choroiditis?
Inflammation of the back chamber of the eye
What group of conditions cause iritis/choroiditis?
Granulomatous disorders- syphilis, TB, sarcoidosis, leprosy, brucellosis and toxoplasmosis
What ocular features may be seen in Reiter’s?
Iritis and/or conjunctivitis
What is episcleritis?
Inflammation of the episclera, which lies between the conjunctiva and the sclera
What conditions may cause episcleritis/scleritis?
RA
Vasculitis
SLE
What is the possible impact of giant cell arteritis on the eye?
Optic nerve ischaemia presenting as sudden blindness
What is keratoconjunctivitis sicca?
A reduciton in tear formation tested by the Schirmer filter paper test (<5mm in 5 minutes). It causes a gritty feeling in the eyes and a dry mouth (xerostomia from reduced saliva production).
In what conditions is keratoconjunctivitis sicca seen?
- May occur on it’s own (Sjogren’s syndrome)
- May occur with other diseases e.g. SLE, RA and sarcoidosis
How is keratoconjunctivitis sicca treated?
Artificial tears/saliva
What causes hypertensive retinopathy?
Increased BP accelerates atherosclerosis in retinal vessels
Describe the appearance of hypertensive retinopathy
- Hardened arteries appear shiny “silver wiring”
- They ‘nip’ veins where they cross (AV nipping)
- Narrowed arterioles may become blocked causing localised retinal infarction seen as cotton wool spots
- Leaks from these in severe hypertension manifest as hard exudates or macular oedema
What might be suggested by papilloedema in the context of retinopathy?
Accelerated hypertension
What sign of infective endocarditis is seen in the eye?
Roth spots- small retinal infarcts
What signs of dermatomyositis are related to the eye?
- Lilac-purple heliotrope rash on the eyelid
- Peri-orbital oedema
- Retinopathy showing cotton-wool spots caused by micro-infarcts
What might be caused by emboli passing through the retinal vasculature?
Retinal artery occlusion- retinal pallor corresponds to the area affected so may be global or segmental
Amaurosis fugax