Syringe Volume Issues

Question 1

Define Syringe Dead Space

Answer 1

Space in a syringe where fluid is retained after the syringe plunger has been depressed

Question 2

Syringe + Needle Volume

Answer 2

Dead space in the syringe hub varies with manufacturers

Question 3

Increased gauge =

Answer 3

decreased needle volume

Question 4

Increased needle length =

Answer 4

increased needle volume

Question 5

Dead Space Considerations

Answer 5

Mixing 2 drugs in 1 syringe & diluting a drug in a syring= significant with less than 1 mL

Question 6

When mixing 2 drugs in 1 syringe:

Answer 6

You will get too much of the first drug and not enough of the second drug

Question 7

Hub holds:

Answer 7

0.4 mL

Question 8

Needle holds:

Answer 8

0.3 mL

Question 9

How to handle dead space in mixing 2 drugs?

Answer 9

Use three syringes - one for each drug and one to mix in

Question 10

You are given a priming volume of 0.5 with 0.1 mL of drug A and 0.1 mL of drug B.
What are the total volumes of drug A, B and total overall?

Answer 10

0. 1/2 = 0.05
1. 1+0.05 = 0.15 Drug A and Drug B
2. 15+0.15= 0.3 mL total

Question 11

You are given a priming volume of 0.1 mL

Calculate the priming volume for 0.3 mL of glycopyrrolate and 0.48 mL of promethazine

Answer 11

0. 1* (0.3/(0.3+0.48)) = 0.04 mL glycopyrrolate

0. 1*(0.48/(0.3+0.48) = 0.06 mL of promethazine