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SEROLOGY > SYPHILIS > Flashcards

SYPHILIS Flashcards

1
Q

Syphilis is cause by?

A

Treponema pallidum

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2
Q

Aka

A

Great imitator

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3
Q

Enumerate stages

A

Primary/ Early
Secondary
Latent/ hidden
Tertiary/ Late

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4
Q

Immunoglobulin that can be seen in primary stage

A

IgM

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5
Q

Signs/Symptoms in primary/early

A

Hard chancer

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6
Q

Signs/Symptoms in Secondary stage

A

Condyloma latum (wart-like lesson)

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7
Q

Immunoglobulin can be seen in Secondary stage

A

IgG

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8
Q

Hard chancer is painful or painless

A

Painless

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9
Q

Soft chancre is caused by

A

H. ducreyi

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10
Q

Signs/Symptoms in Tertiary/ late stage

A

Gummas/ gummatas

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11
Q

Tertiary/ late stage can cause

A

Neurosyphilis or cardiovascular syphilis

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12
Q

Screening test for syphilis (non- treponemal or treponemal)

A

Non-treponemal

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13
Q

Antigen use in screening

A

Cardiolipin

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14
Q

Antibody detected in screening test

A

Reagin

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15
Q

Meaning of VDRL

A

Venereal Disease Research Laboratory

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16
Q

Meaning of RPR

A

Rapid Plasma Reagin

17
Q

Principle of non-treponemal test for syphilis

A

Flocculation ( a precipitation reaction)

18
Q

Reagents of VDRL

A

-Cardiolipin
-Cholesterol
-Lecithin

19
Q

Reagents of RPR

A

-Cardiolipin
-Cholesterol
-Charcoal
-Lecithin

20
Q

Needs serum inactivation (VDRL or RPR)

A

VDRL

21
Q

No serum inactivation (VDRL or RPR)

A

RPR

22
Q

Reads microscopically (VDRL or RPR)

A

VDRL

23
Q

Reads Macroscopically (VDRL or RPR)

A

RPR

24
Q

180 rpm for 4 minutes (VDRL or RPR)

A

VDRL

25
Q

100 rpm for 8 minutes (VDRL or RPR)

A

RPR

26
Q

Gauge of needle use to dispense antigen form a small plastic dispensing bottle (RPR card test)

A

20 gauge

27
Q

Reading and reporting of RPR Card Test. Medium or large clumps

A

Reactive

28
Q

Reading and reporting of RPR Card Test. No clumping ( slightly roughness) + tail upon swirling

A

Nonreactive

29
Q

Reading and reporting of RPR Card Test. Small clumps

A

Weakly reactive

SEROLOGY (3 decks)

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