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SEROLOGY > SYPHILIS > Flashcards

SYPHILIS Flashcards

1
Q

Syphilis is cause by?

A

Treponema pallidum

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2
Q

Aka

A

Great imitator

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3
Q

Enumerate stages

A

Primary/ Early
Secondary
Latent/ hidden
Tertiary/ Late

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4
Q

Immunoglobulin that can be seen in primary stage

A

IgM

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5
Q

Signs/Symptoms in primary/early

A

Hard chancer

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6
Q

Signs/Symptoms in Secondary stage

A

Condyloma latum (wart-like lesson)

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7
Q

Immunoglobulin can be seen in Secondary stage

A

IgG

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8
Q

Hard chancer is painful or painless

A

Painless

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9
Q

Soft chancre is caused by

A

H. ducreyi

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10
Q

Signs/Symptoms in Tertiary/ late stage

A

Gummas/ gummatas

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11
Q

Tertiary/ late stage can cause

A

Neurosyphilis or cardiovascular syphilis

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12
Q

Screening test for syphilis (non- treponemal or treponemal)

A

Non-treponemal

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13
Q

Antigen use in screening

A

Cardiolipin

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14
Q

Antibody detected in screening test

A

Reagin

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15
Q

Meaning of VDRL

A

Venereal Disease Research Laboratory

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16
Q

Meaning of RPR

A

Rapid Plasma Reagin

17
Q

Principle of non-treponemal test for syphilis

A

Flocculation ( a precipitation reaction)

18
Q

Reagents of VDRL

A

-Cardiolipin
-Cholesterol
-Lecithin

19
Q

Reagents of RPR

A

-Cardiolipin
-Cholesterol
-Charcoal
-Lecithin

20
Q

Needs serum inactivation (VDRL or RPR)

21
Q

No serum inactivation (VDRL or RPR)

22
Q

Reads microscopically (VDRL or RPR)

23
Q

Reads Macroscopically (VDRL or RPR)

24
Q

180 rpm for 4 minutes (VDRL or RPR)

25
100 rpm for 8 minutes (VDRL or RPR)
RPR
26
Gauge of needle use to dispense antigen form a small plastic dispensing bottle (RPR card test)
20 gauge
27
Reading and reporting of RPR Card Test. Medium or large clumps
Reactive
28
Reading and reporting of RPR Card Test. No clumping ( slightly roughness) + tail upon swirling
Nonreactive
29
Reading and reporting of RPR Card Test. Small clumps
Weakly reactive

SEROLOGY (3 decks)

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