Synthetic routes - aliphatic compounds Flashcards

1
Q

Alkane to Haloalkane

A

halogen

uv light - free radical substitution

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2
Q

Alkene to alkane

A

H2

Nickle catalyst

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3
Q

Alkene to haloalkane

A

halogen halide

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4
Q

Alkene to alcohol

A

H2O (steam)

H3PO4

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5
Q

Haloalkane to nitrile

A

CN

ethanol

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6
Q

Haloalkane to amine

A

NH2

ethanol

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7
Q

Haloalkane to alcohol

A

NaOH(aq)

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8
Q

Alcohol to haloalkane

A

sodium halide

H2SO4

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9
Q

Alcohol to alkene

A

H2PO4 or H2SO4

heat

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10
Q

Secondary Alcohol to ketone

A

K2Cr2O7/H2SO4,

reflux

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11
Q

Primary alcohol to aldehyde

A

K2Cr2O7/H2SO4

distillation

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12
Q

Aldehyde to primary alcohol

A

NaBH4

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13
Q

Ketone to secondary alcohol

A

NaBH4

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14
Q

Primary alcohol to Carboxylic acid

A

K2Cr2O7/H2SO4

reflux

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15
Q

Alcohol to ester

A

carboxylic acid/conc. H2SO4 OR acid anhydride

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16
Q

Ester to carboxylic acid

A

alcohol / conc H2SO4

17
Q

Carboxylic acid to ester

A

dilute acid

heat

18
Q

Ester to carboxylate ion and alcohol

A

OH-

alkaline hydrolysis

19
Q

Acyl chloride to ester

A

alcohol

20
Q

Acyl chloride to primary amide

A

NH3 or R’NH2

21
Q

Acyl chloride to secondary aminde

A

primary amine

22
Q

Nitrile to carboxylic acid

A

H2O/HCl,

heat

23
Q

Hydroxynitrile to carboxylic acid

A

H2O/HCl,

heat

24
Q

Hydroxynitrile to amine

A

H2/ Nickel catalyst