Synthetic Routes Flashcards

1
Q

Alkane to haloalkane

A

Free radical substitution
Br2, Cl2, etc
UV light

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2
Q

Haloalkane to alcohol

A

Nucleophilic substitution
Aqueous KOH or NaOH
Heat under reflux

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3
Q

Haloalkane to nitrile

A

Nucleophilic substitution
Heat under reflux with KCN dissolved in ethanol

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4
Q

Haloalkane to primary amine to secondary amine

A

Nucleophilic substitution
Heat under reflux with (excess) NH3 dissolved in alcohol

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5
Q

Haloalkane to alkene

A

Elimination
Heat under reflux with ethanolic KOH

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6
Q

Alkene to polyalkene

A

High pressure
Catalyst

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7
Q

Alkene to haloalkane

A

Electrophilic addition
HCl, HBr
Room temp

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8
Q

Alkene to dihalogenoalkane

A

Electrophilic addition
Cl2, Br2
Room temp

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9
Q

Dihalogenoalkane to diol

A

Nucleophilic substitution
Aqueous KOH
Heat under reflux

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10
Q

Alcohol to alkene

A

conc. H2SO4 or conc. H3PO4
Elimination, dehydration

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11
Q

Alkene to alcohol

A

Step 1: Electrophilic addition with H2SO4
Step 2: H2O warm hydrolysis

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