Synthesis Roots: In-Organic Flashcards by Eve Larsen

Q

Ester to sodium salt of carboxylic acid + alcohol

A

NaOH (aq)

alkaline hydrolysis

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Q

Ester to carboxylic acid

A

Dilute acid hydrolysis

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Q

Nitrile to amine

A

H2/Ni

reduction

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Q

Alkene to primary alcohol

A

H3PO4/H2O

hydration

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Q

Nitrile to carboxylic acid

A

H20/HCl

hydrolysis

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Q

Acyl chloride to ester

A

Alcohol

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Q

Haloalkane to amine

A

NH3/Ethanol

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Q

What is a nitrile?

A

Carbon triple bond nitrogen functional group

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Q

Primary alcohol to haloalkane

A

Sodium halide/ H2SO4

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Q

Alkene to haloaalkane

A

Hydrogen halide e.g. HCl

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Q

Haloalkane to primary alcohol

A

NaOH (aq)

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Q

Haloalkane to nitrile

A

NaCN

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Q

Aldehyde to carboxylic acid

A

K2Cr2O7/H+

Oxidation

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Q

Acyl chloride to primary amide

A

NH3

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Q

Acyl chloride to carboxylic acid

A

H2O

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Q

What is an amine?

A

C-NH2

Q

Aldehyde to hydroxynitrile

A

NaCN/H+

Nucleophillic addition

Q

Primary alcohol to alkene

A

H2SO4

Q

Primary alcohol to aldehyde

A

K2Cr2O7/H+

oxidation

Q

Aldehyde to primary alcohol

A

NaBH4/H2O

reduction

Q

Primary alcohol to ester

A

Carboxylic acid/ H2SO4

esterification

Q

Acyl chloride to secondary amide

A

Primary amine

Q

Carboxylic acid to ester

A

Alcohol/H2SO4

esterification

Q

Carboxylic acid to acyl chloride

A

SOCl2

Q

What is an amide?

A

(R)O=C-NH2