Syndromes Flashcards
pharyngitis is caused by __
first line tx is __
second line tx is __
pathogen: group A strep (strep pyogenes)
1st: amoxicillin OR Pen VK
2nd: cephalexin OR macrolide
otitis media is caused by __
1st line tx is __
pathogens: strep pneumo, H.flu, m.catt
1st line tx: amoxicillin
PCN allergy: 2nd and 3rd gen cephalo, macrolides
severe: Augmentin
what is the most common cause of acute otitis media
viruses
celluilitis is caused by __
1st line tx is __
pathogen: s. aureus, GAS
tx MSSA: dicloxacillin OR 1st gen ceph OR clinda
tx MRSA: clindamycin OR sulfa-smx OR doxycycline
GAS: amoxicillin
pyodermas are caused by __
1st line tx is __
pathogens: MSSA, MRSA, GBS
tx MSSA: topical muciporin OR oral dicloxacillin OR oral cephalexin
tx MRSA: TMP-SMX, doxycycline, clindamycin, linezolid
what are some common STDs
neisseria gonorrhoeae
chlamydia trachomatis
mycoplasma hominum
syphilis
trichomonas
what is 1st line tx for neisseria gonorrhoeae
ceftriaxone
what is 1st line tx for chlamydia tracomatis
azithromycin/doxycycline
what is 1st line tx for mycoplasma hominum
azithromycin/dozycycline
what is 1st line tx for trichomonas
metronidazole
what is 1st line tx for CDAD
vancomycin
metronidazole
intraabdominal infxns are caused by __
1st line tx is __
pathogens: e.coli and other (-) rods, bacteroides fragilis
e.coli tx: 2nd and 3rd gen cephalo
bacteroides fragilis: pip taz/metronidazole
CAP is caused by __
1st line tx is __
pathogens: strep pneumo, mycoplasma, chlamydophila pneumoniae
tx strep pneumo no comorbidities: amoxicillin
tx strep pneumo w. comorbidities: doxycycline OR macrolide
tx strep pneumo w. comorbidities: augmentin
tx mycoplasma or chlamydophila pneumo: doxycycline OR azithromycin
healthcare associated pna is caused by __
first line tx is __
pathogens: MRSA, pseudo, e.coli
tx MRSA: vancomycin
tx pseudo: pip-taz
tx e.coli: 2nd and 3rd gen cephalo
uncomplicated UTIs (cystitis) are caused by __
1st line tx is __
pathogens: e.coli, other (-) rods
tx: trimeth-sulf, nitro
complicated UTIs are caused by __
1st line tx is __
pathogens: e.coli, pseudo, MRSA
e.coli tx: 2nd/3rd gen cephalo
pseudo tx: cipro or levo, aminoglycosides
MRSA tx: vanco
complicated UTIs are generally caused by __
examples include __
and __
gram (-)
cystitis
pyelonephritis
cystitis tx
cipro or levo
aminogylcoside
ceftriaxone
pyelonephritis tx
empiric: cipro or levo
post culture: pip taz, amp-gent, 3rd gen cephalo
bacterial sinusitis is caused by __
1st line tx is __
pathogens: h.flu, m.catt
1st line tx: Augmentin
if recent abx: Augmentin, FQ, 2nd/3rd gen cephallo
PCN allergy: macrolides
acute bacterial bronchitis is caused by __
1st line tx is __
pathogens: mycoplasma, c. pneumo, bortadella
tx: no abx in healthy pt!
which penicillin is penicillinase resistant
dicloxacillin
clindamycin selectively distributes in
bones
macrolides selectively distribute into
pulmonary cells (URIs PNA)
tetracyclines selectively distribute into
gingival crevicular fluid and sebum (peridonitis and acne)
nitrofurantoin selectively distributes into
urine → UTIs
which abx has excellent CNS distribution
ceftriaxone