Syndrome of inappropriate ADH secretion Flashcards
1
Q
What is it?
A
Hyponatraemia caused by inappropriate secretion of ADH
2
Q
Management
A
Fluid restriction
If this doesnt work:
- Demelocycline
- Tolvaptan
3
Q
Demelocycline
A
Blocks renal tubular effect of ADH
4
Q
Tolvaptan
A
Vasopressin antagonist
5
Q
Caution
A
Avoid rapid correction of hyponatraemia - causes osmotic demyelination of neurones = SERIOUS CNS SIDE EFFECTS