synaptic transmission I Flashcards
1
Q
steps of synaptic transmission?
A
- transmitter is synthesized and stored in vesicles
- action potential invades the presynaptic terminal
- depolarization of presynaptic terminal causes opening of voltage-gated Ca2+ channels
- influx of Ca2+ through channels
- Ca2+ causes vesicles to fuse with presynaptic membrane
- transmitter is released into synaptic cleft via exocytosis
- transmitter binds to receptor molecules in postsynaptic membranes
- opening or closing of postsynaptic channels
- postsynaptic current causes excitatory or inhibitory postsynaptic potential that changes the excitability of the postsynaptic cell
- removal of neurotransmitter by glial uptake or enzymatic degradation
- retrieval of vesicular membrane from plasma membrane