Synaptic Transmission Flashcards
Once in the presynaptic terminal, the action potential triggers the opening of ___ voltage-gated channels
Calcium (Ca+)
When the Ca+ voltage-gated channels are open _____ enters to enter
Calcium
Calciums that enters through Ca+ voltage-gated ion channels will act as a secondary messenger.
True or False
True
Neurotransmitters will bind to the secondary messenger in the _______.
Synaptic Cleft
Artificially injecting Ca+ into the terminal would trigger a neurotransmitter release. Even without an action potential.
True or False
True
Once the Neurotransmitter is in the synaptic cleft, it will bind to the post-synaptic _____ receptor
Ionotropic
The message is terminated by _____ in the synaptic cleft
enzymes
The message (neurotransmitter) is terminated by ______ in the presynaptic terminal
endocytosis
To be classified as a neurotransmitter a molecule must (2)
- Be released by the presynaptic action
potential - Have a post-synaptic receptor
The 2 most common neurotransmitter in the CNS are:
Glutamate (excitatory)
GABA (inhibitory)
_____ is the neurotransmitter found at the neuromuscular junction
Acetylcholine (ACh)
Ionotropic receptors are _____ of the ion channel
part
Metabotropic receptors are _____ of the ion channel and acts through metabolic pathway.
separate