Synaptic Transmission

Question 1

what mediate fast neural communication

Answer 1

transmitter-gated ion channels

Question 2

overview of synaptic transmission

Answer 2

pre synaptic AP
Ca2+ influx
vesicular transmitter release
activation of transmitter gated ion channels
post synaptic depolarisation

Question 3

vesamicol action

Answer 3

inhibits vesicular uptake of ACh
decreases amplitude of mepps

Question 4

α-latrotoxin action
why does it cause a distended terminal

Answer 4

binds post synaptic receptors and forms a cation conducting pore
vesicles are not endocytosed after emptying

Question 5

what does Ca2+ cause at the NMJ

Answer 5

vesicle fusion with the membrane and exocytosis of n-t