Synapse Flashcards
What are the two neurotransmitters in the body?
Excitatory and inhibitory neurotransmitters
Transmission of nerve impulses across a Synaptic cleft is carried out by chemicals called _________________________.
Neurotransmitters substances
If the neurotransmitter is received by the postsynaptic fiber…
It will fire 100%
Neurotransmitters substances are stored where?
In the vesicles at the end of the axon
Find impulse reaches the end of the axon, and Na+ and Ca+2 come into the axon, the calcium binds with ________________ that pull the neurotransmitter vesicles to the presynaptic membrane surface. The vesicles and join to the _____________, forcing the neurotransmitters into the cleft(exocytosis). The neurotransmitters defuse across…
Contractile proteins,
Join to the cell membrane
Diffuse across the synaptic gap
A neurotransmitter only has a….
Short period to work once it’s been released into the synaptic cleft.
The neurotransmitter binds to _______________ on the dendrite of the next neuron. If enough transmitter substance is received the neuron will _______ and continue the impulse.
Bind to specific receptor sites,
“Fire”
What happens to the neurotransmitter once it’s been released into the synaptic cleft?
Enzymes rapidly break down the transmitter substance to clear the synapse so the next impulse can be transmitted
What are examples of neurotransmitters that speed up and slow down activity?
Noradrenaline- speeds up activity
Acetylcholine- slows down activity
How does each axon end?
Each axon branches off and ends with a swelled tip or terminal knob that lies close to you but not touching the dendrite of another neuron (or an organ). The entire region is called a synapse
How does Tylenol work?
Painkiller such as Tylenol act as an enzyme to break down the neurotransmitter to decrease the pain impulse
What is the neurotransmitters job?
Is to increase the permeability of the sodium ions on the postsynaptic membrane
If not enough substance is received…
It will not fire at all
What is it called when two excitatory neurotransmitters work together?
They cause an action potential that is called summation
What are two main examples of enzymes that break down the transmitter substance?
Monoamine oxidase breaks down noradrenaline
And
Acetylcholinesterase breaks down acetylcholine