Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Symptoms and causes > Symptoms and treatment > Flashcards

Symptoms and treatment Flashcards

1
Q

1/3 makes have jaundice

Majority are asymptomatic

Neonatal hyperbolirubinea

Acute/chronic HA

A

G6PD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Remove triggers to remove HA by decreasing ROS Chance

Remove fava beans

Remove medication (dapsone)

A

G6PD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What drug is increases ROS Chance

A

Dapsone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Jaundice

Splenegamoly

Extramedary hematopoiesis

Hepatosplengamoly

A

Autoimmune HA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Prednisone

Corticosteroids

Cytotoxic immunosuppresive drugs

Cyclosporine

Splenectomy if corticosteroids dont work 3months

Monoclonal AB

A

Autoimmune HA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Monoclonal AB treatment for aHA

A

Campath 1H

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Why does harmolysis occur in RBC in HbH disease

A

Excess of B globin /homotetramer (HbH)

Recognised by spleen and destroyed

Extravascular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Hepatosplenomegaly

Ineffective haemopoirsis

A

HbH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Treatment generally not required

Antibiotics

Regular folic acid if preganant

Splenectomy

BT

A

HbH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Vado-occlusive

Severe bone/joint pain

Acute chest syndrome

Dactylitis (children)

Jaundice

Gall stones

Splenegomaly

A

Sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Life long prophylactic penicillin with folate replacement

Avoid triggers if trait (altitude.stress)

Blood transfusions +iron chelation

HSCT

Hydroxurea

Mumurs / hamaturia/renal tubular defects /strokes

A

Sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does hydroxurea do

What’s it used in

A

Increase HbF

Sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What bacterial infection is common in sickle cell patients

A

Staphylococcus aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Avascular Necrosis if head of femur / growth retardation

A

Sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Parlour of mucuos membrane

Conjunctival mucosa

Brittle nails

Ulceration around mouth

Glottitis

Jaundice

A

IDA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ferrous sulphate

Original cause dealt with

A

IDA

17
Q

How much ferrous sulphate given to IDA patient

A

100-200mg daily

Rise of 2g/dl for 3wks

18
Q

Sclera of rye

Glossitis

Jaundice

A

Megaloblastic anaemia

19
Q

6x1000ug 2/3wks

1000ug/3months maintenance dose

A

B12

20
Q

How long does it take to reach normal haemoglobin levels with treatment of b12

A

60 days

21
Q

5mg daily 4months of b12

A

Folate deficiency

22
Q

Pallor /jaundice /splenomegaly /family history

A

Herdiatory spherocytosis

23
Q

Splenectomy

Partial cholecystectomy for fall stones

Phototherapy for neonatal jaundice

A

Herdatory spherocytosis

24
Q

Erythroid hyperplasia anaemia

Cholelithiasis (gall stones)

Iron overload

Bacterial infection

Helatosplenomegaly

Recurrent leg ulcers

A

B-thala major

25
Q

Why does iron overload exist for b thala

A

Increased absorption

Multiple blood transfusions

26
Q

Blood transfusions

Infections dealt with(ab)

Splenectomy

HSCT

Long term folic Acid + gene therapy

A

B major thala

27
Q

What infections are b thala prone to

A

Klebsiella

28
Q

Why does increase bone marrow occur in b thala

A

Increased EPO release

Symptoms and causes (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions