Sympatholytics(AABs)-ATI Pharm

Question 1

AAB’s stand for

Answer 1

Alpha adrenergic blockers

Question 2

Meds

Answer 2

Prototype=prazosin

• doxazosin
• terazosin

Question 3

Expected pharm actions

Answer 3

Selective alpha,blockade results in the following
1-venous and arterial dilation
2-smooth muscle relaxation of prostatic capsule and bladder neck

Question 4

Therapeutic uses

Answer 4

primary hypertension
Doxazosin/terazosin
1-decrease manifestations of benign prostatic hyperplasia(BPH) which include urgency,frequency,and dysuria

Question 5

Complications

Answer 5

1-first dose orthostatic hypotension;first dose given at night

Question 6

Contraindications/precautions

Answer 6

Pregnancy risk cat C
Contraindicated in pts w/hypotension
Use cautiously in pts w/angina pectoris or renal insufficiency and in older adults

Question 7

Interactions

Answer 7

1-antihypertensive meds have an additive effect

Question 8

Nursing admin

Answer 8

1-can be taken with food
2-take dose at bedtime to decrease first dose hypotensive effect
3-safety measures to minimize effect of orthostatic hypotension