sympathetic nervous system Flashcards
what is a synapse?
Where two groups of neurons are linked together
A collection of synapses is referred to as a?
ganglion
Neurons that emerge from the CNS form the ?
Preganglionic fiber
Neurons that travel from the ganglion to the internal organ for the?
postganglionic nerve fiber
what is the autonomic ganglion?
the collection of synapses between the preganglionic and the postganglionic fibers
The SNS increases the activity of certain organs why?
to allow for greater expenditure of energy for both physical and mental exertion
***for example sympathetic stimulation increases heart rate and the force of myocardial contraction***
The PSNS division is more active during periods of?
rest and restoration of body energy stores
The PSNS increases which body functions?
digestion and elimination of waste products
The SNS and PSNS release which neurotransmitter from the preganglionic neuron?
acetylcholine
What gives the SNS and PSNS their unique functionalities?
they release different neurotransmitters from their postganglionic neurons
What is the neurotransmitter that is released at the postganglionic nerve endings of the PSNS?
acetylcholine
The PSNS postganglionic nerve endings are called what and why?
Chloinergic or muscarinic, because they release the neurotransmitter acetylcholine
The SNS postganglionic nerve endings release what neurotransmitter?
norephinephrine
the primary function of the nervous system is to?
control and coordinate the activity of all the systems within our body
the SNS postganglionic nerve endings are known are known as what and why?
adrenergic, because they release norepinephrine
The nervous system is divided into what two systems?
the central nervous system and the peripheral nervous system
The CNS has what structures within it?
the brain and spinal cord
The peripheral nervous system is divided into what two systems?
the somatic nervous system and the autonomic nervous system
The somatic nervous system is also called the?
voluntary nervous system
The somatic nervous system is responsible for what?
conscious control of skeletal muscles
The autonomic nervous system regulates what?
involuntary activities of the internal organs and glands
The autonomic nervous system is broken into what two systems?
the sympathetic nervous system and the parasympathetic nervous system
The ANS is composed of what?
nerves that innervate smooth and cardiac muscle
The smooth and cardiac muscle (involuntary muscle) are found in the walls of our internal organs and glands and possess a special property called?
autorhythmicity
Autorhythmicity allow smooth and cardiac muscles to initate their own what?
contractions
if internal organs can initate their own contractions why is the ANS even needed? What is the primary function of the ANS?
regulate the rate at which these organs are working either by increasing or decreasing their activity to maintain homeostasis.
The body maintains homeostasis by balancing what two systems?
SNS and PSNS
**the general plan is that one division is responsible for increasing the activity of a particular organ while the other division decreases the activity of that same organ; however this isn’t a precise science and so this doesn’t always hold 100% true
the effects of the PSNS are produced by the release of _______ which binds to the ________ or _______ receptors.
acetylcholine
cholinergic or muscarinic receptors
the effects of the SNS stimulation are produced by the release of ______ from _______ nerve endings and by ______ which is released from the adrenal medulla.
norepinephrine
adrenergic nerve endings
epinephrine
Both norepinephrine and epinephrine bind to and stimulate _____ receptors.
adrenergic
The adrenergic receptors are divided into two types of receptors, which are?
alpha and beta receptors
The adrenergic receptors are further subdivided what receptors?
Alpha 1 and Alpha 2 receptors
The beta receptors are further subdivided into what receptors?
Beta 1 and 2 receptors
although some organs contain more than one type of receptor, one receptor usually does what?
predominates and determines the overall response of the organ
_______ is taken up into the nerve ending and is enzymatically converted to DOPA.
typrosine
DOPA is then converted into ___________.
dopamine
Dopamine enters storage vesicles where it is stored as _______ until it is needed to be released later.
norepinephrine
Upon adrenergic stimulation, ________ is released from the adrenergic nerve ending into the _______ ______.
norepinephrine
synaptic cleft
Once norepinephrine is released from the adrenergic nerve ending into the synaptic cleft, it can stimulate different receptors such as? where are they located ? and what happens?
Alpha 2 receptors, located in the postganglioninc neuron, inhibiting further release of norepinephrine.
Alpha 1 receptors, located on the effector organ, stimulating a contraction of smooth muscle response
Beta 1 receptors, located on the effortor organ, stimulating a cardiac response
Norephinephrine can undergo it reuptake which means what? or if the norephinephrine is not reuptaked what can happen to it?
the norephinephrine can go back into the nerve ending where it can be restored in the vesicles (where it is stored when it is converted from dopamine to norephineprhine)
IT CAN BE METABOLIZED VIA MONOAMINE OXIDASE (MAO) INTO INACTIVE METABOLITES
alpha 1 adrenergic receptors are found predominantly on what?
smooth muscle membranes of arteries, veins, and sphincters of the urinary and gastrointestinal tract
When the alpha 1 receptors are stimulated by norephinerine what happens?
smooth muscle contraction
So Alpha 1 receptors stimulated would cause what to happen to the BP, cardiac contractility, and pupils?
increase in BP
increase in myocardial contraction of the heart
pupillary dilation of the eye
alpha one receptor stimulation would do what to the bladder and prostate?
relax the bladder
contract the prostate